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Structural Insights into How Protein-Protein Interaction Modulates the Action of MEK Inhibitors

Published online by Cambridge University Press:  30 July 2021

Zaigham Khan ,
William Marsiglia ,
Arthur Chow ,
Alex Scopton  and
Arvin Dar
Zaigham Khan
Affiliation:
Mount Sinai School of Medicine, New York, United States, Fort Lee, New Jersey, United States
William Marsiglia
Affiliation:
Mount Sinai School of Medicine, New York, United States, New Jersey, United States
Arthur Chow
Affiliation:
Mount Sinai School of Medicine, New York, United States, United States
Alex Scopton
Affiliation:
Mount Sinai School of Medicine, New York, United States, United States
Arvin Dar
Affiliation:
Mount Sinai School of Medicine, New York, United States, United States

Abstract

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Type
Michael Rossmann Memorial Symposium
Information
Microscopy and Microanalysis , Volume 27 , Supplement S1 , August 2021 , pp. 1716 - 1718
Copyright
Copyright © The Author(s), 2021. Published by Cambridge University Press on behalf of the Microscopy Society of America

References

Khan, Zaigham et al. Structural basis for the action of the drug trametinib at KSR-bound MEK. Nature; 588: 509-514 (2020) [PMID: 32927473]CrossRefGoogle ScholarPubMed