Hostname: page-component-586b7cd67f-2plfb Total loading time: 0 Render date: 2024-11-26T18:31:15.886Z Has data issue: false hasContentIssue false
  • English
  • Français

Structural and functional analysis of p47 cofactor binding on the p97 disease mutant

Published online by Cambridge University Press:  30 July 2021

Purbasha Nandi ,
Po-Lin Chiu ,
Tsui-Fen Chou ,
Yu-Ping Poh ,
Feng Wang ,
Shan Li ,
Rod Columbres ,
Dewight Williams  and
Andrey Malyutin
Purbasha Nandi
Affiliation:
Arizona State University, Tempe, Arizona, United States
Po-Lin Chiu
Affiliation:
Arizona State university, Tempe, Arizona, United States
Tsui-Fen Chou
Affiliation:
Caltech, United States
Yu-Ping Poh
Affiliation:
Arizona State University, Tempe, Arizona, United States
Feng Wang
Affiliation:
Caltech, United States
Shan Li
Affiliation:
Caltech, United States
Rod Columbres
Affiliation:
caltech, United States
Dewight Williams
Affiliation:
Arizona State University, Arizona, United States
Andrey Malyutin
Affiliation:
Caltech, United States

Abstract

An abstract is not available for this content so a preview has been provided. As you have access to this content, a full PDF is available via the ‘Save PDF’ action button.
Image of the first page of this content. For PDF version, please use the ‘Save PDF’ preceeding this image.'
Type
Cryo-EM at Local, Regional, and National Cryo-EM Centers
Information
Microscopy and Microanalysis , Volume 27 , Supplement S1 , August 2021 , pp. 1908 - 1910
Copyright
Copyright © The Author(s), 2021. Published by Cambridge University Press on behalf of the Microscopy Society of America

References

Koller, K. J. & Brownstein, M. J. Use of a cDNA clone to identify a supposed precursor protein containing valosin. Nature 325, 542-545, doi:10.1038/325542a0 (1987).Google ScholarPubMed
Peters, J. M., Walsh, M. J. & Franke, W. W. An abundant and ubiquitous homo-oligomeric ring-shaped ATPase particle related to the putative vesicle fusion proteins Sec18p and NSF. EMBO J. 9, 1757-1767 (1990).CrossRefGoogle Scholar
Buchberger, A., Schindelin, H. & Hänzelmann, P. Control of p97 function by cofactor binding. FEBS Lett. 589, 2578-2589, doi:10.1016/j.febslet.2015.08.028 (2015).CrossRefGoogle ScholarPubMed
Meyer, H., Bug, M. & Bremer, S. Emerging functions of the VCP/p97 AAA-ATPase in the ubiquitin system. Nat. Cell Biol. 14, 117-123, doi:10.1038/ncb2407 (2012).CrossRefGoogle ScholarPubMed
Stolz, A., Hilt, W., Buchberger, A. & Wolf, D. H. Cdc48: a power machine in protein degradation. Trends Biochem. Sci. 36, 515-523, doi:10.1016/j.tibs.2011.06.001 (2011).CrossRefGoogle Scholar
Yeung, H. O. et al. Insights into adaptor binding to the AAA protein p97. Biochem Soc Trans 36, 62-67, doi:10.1042/BST0360062 (2008).CrossRefGoogle Scholar
Kondo, H. et al. p47 is a cofactor for p97-mediated membrane fusion. Nature 388, 75-78, doi:10.1038/40411 (1997).CrossRefGoogle ScholarPubMed