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EM Study of Gastric Tumor Microvasculature
Published online by Cambridge University Press: 02 July 2020
Extract
It has been considered that the behavior of tumors is consistent with the concept that tumor growth is angiogenesis dependent. However, additionally to the newly formed vessels other patterns of tumor capillaries have been described. Information concerning the ultrastructure of tumor blood vessels has been obtained mostly from experimental models. With regard to human tumors, since no systematic ultrastructural studies are available on the gastric tumor microvasculature, the aim of the present work was to characterize the vascular architecture of this type of tumor.
Surgically resected specimens were obtained in tumors from five patients (three males and two females) between 45 to 66 years of age (mean, 56.2 years), with a histopathological diagnosis of moderately differentiated gastric adenocarcinoma. Immediately after resection, tissue samples taken from areas of tumor center were processed by routine transmission electron microscopy techniques and observed in a Hitachi H-500 EM.
The microvasculature within gastric adenocarcinomas was characterized by newly formed capillaries with proliferative endothelial cytoplasm (Fig. 1).
- Type
- Imaging Cells and Organelles
- Information
- Microscopy and Microanalysis , Volume 3 , Issue S2: Proceedings: Microscopy & Microanalysis '97, Microscopy Society of America 55th Annual Meeting, Microbeam Analysis Society 31st Annual Meeting, Histochemical Society 48th Annual Meeting, Cleveland, Ohio, August 10-14, 1997 , August 1997 , pp. 259 - 260
- Copyright
- Copyright © Microscopy Society of America 1997