Hostname: page-component-586b7cd67f-t7czq Total loading time: 0 Render date: 2024-12-02T23:33:34.344Z Has data issue: false hasContentIssue false
  • English
  • Français

CryoEM Reveals Multi-step Activation of γTubulin and Assemblies to Optimize Microtubule Nucleation

Published online by Cambridge University Press:  05 August 2019

Axel Brilot  and
David A. Agard
Axel Brilot
Affiliation:
Department of Biochemistry and Biophysics and the Howard Hughes Medical Institute, University of California, San Francisco, California, USA.
David A. Agard*
Affiliation:
Department of Biochemistry and Biophysics and the Howard Hughes Medical Institute, University of California, San Francisco, California, USA.
*
*Corresponding Author: [email protected]

Abstract

An abstract is not available for this content so a preview has been provided. As you have access to this content, a full PDF is available via the ‘Save PDF’ action button.
Image of the first page of this content. For PDF version, please use the ‘Save PDF’ preceeding this image.'
Type
3D Structures: from Macromolecular Assemblies to Whole Cells (3DEM FIG)
Information
Microscopy and Microanalysis , Volume 25 , Supplement S2 , August 2019 , pp. 1298 - 1299
Copyright
Copyright © Microscopy Society of America 2019 

References

[1]Desai, A and Mitchison, TJ, Annu. Rev. Cell Dev. Biol. 13, (1997), p. 83.Google Scholar
[2]Vinh, DBN et al. , Molecular Biology of the Cell 13 (2002), p.1144.Google Scholar
[3]Kollman, J et al. , Nat. Struct. Mol. Biol. 22 (2002), p. 132.Google Scholar
[4]Knop, M and Schiebel, E, EMBO J 16 (2002), p. 6985.Google Scholar
[5]Kollman, J et al. , Nature 466 (2010), p. 879.Google Scholar
[6]Lyon, A et al. , Molecular Biology of the Cell 27 (2016), p. 2245.Google Scholar
[7]We acknowledge financial support from the following sources: Howard Hughes Medical Institute (DAA), National Institute of General Medical Sciences (NIGMS) grants: R01 GM031627, R35GM118099 and P01 GM105537. We gratefully acknowledge many helpful discussions with members of the Agard lab, as well as with our collaborators on the Yeast Centrosome – Structure, Assembly, and Function program project grant in the labs of Trisha Davis, Chip Asbury, Ivan Rayment, Andrej Sali, Mark Winey, and Sue Jaspersen.Google Scholar