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Characterization of ER-mitochondria contact sites using cryo-CLEM

Published online by Cambridge University Press:  30 July 2021

Reza Paraan ,
Victoria Hewitt ,
Yusuke Hirabayashi ,
Franck Polleux ,
Clint Potter  and
Bridget Carragher
Reza Paraan
Affiliation:
New York Structural Biology Center, United States
Victoria Hewitt
Affiliation:
Columbia University, United States
Yusuke Hirabayashi
Affiliation:
University of Tokyo, United States
Franck Polleux
Affiliation:
Columbia University, United States
Clint Potter
Affiliation:
New York Structural Biology Center, New York, New York, United States
Bridget Carragher
Affiliation:
New York Structural Biology Center, New York, New York, United States

Abstract

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Type
3D Structures: From Macromolecular Assemblies to Whole Cells (3DEM FIG)
Information
Microscopy and Microanalysis , Volume 27 , Supplement S1 , August 2021 , pp. 1712 - 1713
Copyright
Copyright © The Author(s), 2021. Published by Cambridge University Press on behalf of the Microscopy Society of America

References

Area-Gomez, E, Schon, EA. Mitochondria-associated ER membranes and Alzheimer disease. Curr Opin Genet Dev. 2016 Jun;38:90-96. doi: 10.1016/j.gde.2016.04.006. Epub 2016 May 25. PMID: 27235807; PMCID: PMC5390896.Google ScholarPubMed
Hirabayashi, Y., Kwon, S. K., Paek, H., Pernice, W. M., Paul, M. A., Lee, J., … & Polleux, F. (2017). ER-mitochondria tethering by PDZD8 regulates Ca2+ dynamics in mammalian neurons. Science, 358(6363), 623-630.Google ScholarPubMed
Kornmann, B, Currie, E, Collins, SR, Schuldiner, M, Nunnari, J, Weissman, JS, Walter, P. An ER-mitochondria tethering complex revealed by a synthetic biology screen. Science. 2009 Jul 24;325(5939):477-81. doi: 10.1126/science.1175088. Epub 2009 Jun 25. PMID: 19556461; PMCID: PMC2933203.CrossRefGoogle ScholarPubMed
Paillusson, S, Stoica, R, Gomez-Suaga, P, Lau, DHW, Mueller, S, Miller, T, Miller, CCJ. There's Something Wrong with my MAM; the ER-Mitochondria Axis and Neurodegenerative Diseases. Trends Neurosci. 2016 Mar;39(3):146-157. doi: 10.1016/j.tins.2016.01.008. Epub 2016 Feb 15. PMID: 26899735; PMCID: PMC4780428.CrossRefGoogle ScholarPubMed