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Advanced In-situ Liquid Phase Transmission Electron Microscopy: A Powerful Tool for Pharmaceutical Studies and Life Science Applications

Published online by Cambridge University Press:  22 July 2022

Hongyu Sun ,
Cliff Mathisen ,
Eva Bladt  and
H. Hugo Pérez-Garza
Hongyu Sun
Affiliation:
DENSsolutions B.V., Delft, Zuid Holland, The Netherlands
Cliff Mathisen
Affiliation:
Nanoscience Instruments, Alexandria VA, USA
Eva Bladt
Affiliation:
DENSsolutions B.V., Delft, Zuid Holland, The Netherlands
H. Hugo Pérez-Garza*
Affiliation:
DENSsolutions B.V., Delft, Zuid Holland, The Netherlands
*
*Corresponding author: [email protected]

Abstract

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Type
On Demand - Imaging, Microscopy, and Micro/Nano-Analysis of Pharmaceutical, Biopharmaceutical, and Medical Health Products - Research, Development, Analysis, Regulation, and Commercialization
Information
Microscopy and Microanalysis , Volume 28 , Supplement S1 , August 2022 , pp. 1440 - 1442
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Copyright
Copyright © Microscopy Society of America 2022

References

Beker, A F et al. , “In situ electrochemistry inside a TEM with controlled mass transport” Nanoscale, 12, 22192-22201 (2020)10.1039/D0NR04961ACrossRefGoogle ScholarPubMed
Battaglia, G et al. , “4D imaging of soft matter in liquid water” (2021), DOI: 10.1101/2021.01.21.42761310.1101/2021.01.21.427613CrossRefGoogle Scholar
Ruiz-Pérez, L et al. , “Imaging protein conformational space in liquid water” (2021), DOI: https://doi.org/10.21203/rs.3.rs-701802/v1CrossRefGoogle Scholar
Cookman, J, Hamilton, V, Price, L S, Hall, S R and Bangert, U, “Visualising early-stage liquid phase organic crystal growth via liquid cell electron microscopy” Nanoscale, 7 (2020).Google Scholar
Cookman, J, Hamilton, V, Hall, S R et al. “Non-classical crystallisation pathway directly observed for a pharmaceutical crystal via liquid phase electron microscopy” Scientific Reports, 10, 19156 (2020). https://doi.org/10.1038/s41598-020-75937-2CrossRefGoogle ScholarPubMed
Ianiro, A, Wu, H, van Rijt, M M J, et al. “Liquid–liquid phase separation during amphiphilic self-assembly”, Nature Chemistry, 11, 320–328 (2019), https://doi.org/10.1038/s41557-019-0210-4CrossRefGoogle ScholarPubMed
Rizvi, A, Mulvey, J T, Patterson, J P, “Observation of Liquid–Liquid-Phase Separation and Vesicle Spreading during Supported Bilayer Formation via Liquid-Phase Transmission Electron Microscopy”, Nano Letters, 21, 24, 10325–10332 (2021).10.1021/acs.nanolett.1c03556CrossRefGoogle Scholar