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A prospective randomised controlled clinical trial to evaluate three immobilisation devices for intra-thoracic radiation therapy

Published online by Cambridge University Press:  07 July 2010

Evelyn O'Shea*
Affiliation:
Radiotherapy Department, St. Luke’s Hospital, Dublin, Ireland
John Armstrong
Affiliation:
Radiotherapy Department, St. Luke’s Hospital, Dublin, Ireland
Charles Gillham
Affiliation:
Radiotherapy Department, St. Luke’s Hospital, Dublin, Ireland
Roisin McCloy
Affiliation:
Radiotherapy Department, St. Luke’s Hospital, Dublin, Ireland
Rachel Murrells
Affiliation:
Radiotherapy Department, St. Luke’s Hospital, Dublin, Ireland
Tom O'Hara
Affiliation:
Infosight Training & Consultancy, Athlone, Ireland
Angela Clayton-Lea
Affiliation:
Radiotherapy Department, St. Luke’s Hospital, Dublin, Ireland
Michael Murphy
Affiliation:
Radiotherapy Department, St. Luke’s Hospital, Dublin, Ireland
Patricia Browne
Affiliation:
Radiotherapy Department, St. Luke’s Hospital, Dublin, Ireland
Catherine Booth
Affiliation:
Radiotherapy Department, St. Luke’s Hospital, Dublin, Ireland
Pierre Thirion
Affiliation:
Radiotherapy Department, St. Luke’s Hospital, Dublin, Ireland
*
Correspondence to: Evelyn O'Shea, Radiotherapy Research & Development Manager, Radiotherapy Department, St. Luke’s Hospital, Rathgar, Dublin 6, Ireland. Email: Evelyn.O'[email protected]

Abstract

Purpose: To determine the optimal of three immobilisation devices for lung radiotherapy in terms of set-up reproducibility, patient comfort, radiation therapists’ (RTs) satisfaction and cost-effectiveness.

Materials and methods: A total of 30 lung CRT patients were randomised to one of three immobilisation techniques – Arm A, headsponge; Arm B, BreastBoard dedicated immobilisation device; and Arm C, LungBoard dedicated immobilisation device.

Results: Random errors were larger for Arm A versus C in all directions (p < 0.05). Random errors were larger for Arm A versus B for y and z directions (p < 0.05). When the data for the immobilisation devices (Arms B+C) were pooled and compared with Arm A (no dedicated device), the systematic errors were larger in the z direction for A (p < 0.05). Arm C was cheaper and was more comfortable for patients. Therapists preferred this device (Arm C) and treatment times were less (p < 0.05).

Conclusion: This is the first prospective randomised controlled lung immobilisation trial, based on 3-DCRT, that takes into account treatment accuracy, users satisfaction and resource implications. It suggests that the LungBoard immobilisation device is optimal.

Type
Original Article
Copyright
Copyright © Cambridge University Press 2010

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