In the article on General Paralysis in the “Nouveau Dictionnaire de Médicine et de Chirurgie Pratiques “(vol. xvi, p. 89., 1878), I thought I had settled the differential diagnosis of this affection when I said:—

“Multiple tumours of the brain, especially those of a syphilitic character, may be accompanied by motor and mental symptoms identical with those of general paralysis. More than once we have observed cases of this kind, and we believe that some do occur in which the differential diagnosis is impossible, except, perhaps, by means of the history. The autopsy alone discloses the error which has existed during the whole duration of the affection.”