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A Controlled Study of the Effectiveness of Nialamide (“Niamid”) in Schizophrenia

Published online by Cambridge University Press:  08 February 2018

J. G. Hegarty ,
A. R. Dabbs  and
R. T. St. Blaize-Molony
J. G. Hegarty
Affiliation:
Oakwood Hospital, Maidstone, Kent
A. R. Dabbs
Affiliation:
Oakwood Hospital, Maidstone, Kent
R. T. St. Blaize-Molony
Affiliation:
Oakwood Hospital, Maidstone, Kent
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Extract

Nialamide is claimed to inhibit the activity of the enzyme monoamine oxidase which is known to be responsible for the breakdown by catalytic oxidation of various amines, e.g. serotonin and norepinephrine. It has been suggested that depression may be associated with inadequate levels of serotonin and/or norepinephrine and that the administration of a monoamine oxidase inhibitor should rationally help to relieve depression. No serious side-effects have been reported in the available literature except that agitated patients might become somewhat more agitated and overactive.

Type
Original Articles
Information
Journal of Mental Science , Volume 107 , Issue 448 , May 1961 , pp. 572 - 574
Copyright
Copyright © Royal College of Psychiatrists, 1961 

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References

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