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Ultrasonically accelerated synthesis of hydroxyapatite

Published online by Cambridge University Press:  31 January 2011

Y. Fang ,
D.K. Agrawal ,
D.M. Roy ,
R. Roy  and
P.W. Brown
Y. Fang
Affiliation:
Materials Research Laboratory, The Pennsylvania State University, University Park, Pennsylvania 16802-4801
D.K. Agrawal
Affiliation:
Materials Research Laboratory, The Pennsylvania State University, University Park, Pennsylvania 16802-4801
D.M. Roy
Affiliation:
Materials Research Laboratory, The Pennsylvania State University, University Park, Pennsylvania 16802-4801
R. Roy
Affiliation:
Materials Research Laboratory, The Pennsylvania State University, University Park, Pennsylvania 16802-4801
P.W. Brown
Affiliation:
Materials Research Laboratory, The Pennsylvania State University, University Park, Pennsylvania 16802-4801
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Abstract

Ultrasonic energy was used to accelerate the formation of hydroxyapatite (HAp). The experiments were carried out in aqueous systems on two different sets of reactants: (1) a mixture of Ca4(PO4)2O(TetCP) and CaHPO4 · 2H2O (brushite) and (2) α–Ca3(PO4)2 (α–TCP). The reaction systems were exposed to ultrasound of 20 kHz for various times ranging from 5 to 80 min. The products were characterized by XRD and SEM. Parallel experiments without ultrasound were carried out for calibration. The results show that the ultrasound substantially accelerates both reactions. With ultrasound, the time required for the TetCP-brushite system to complete the reaction forming HAp was reduced from 9 h to 25 min at 25 °C, and from 3 h to 15 min at 38 °C. At 87 °C, α–TCP does not hydrolyze within 1 h in de-ionized water unless the pH is adjusted. Hydrolysis of α–TCP was induced by sonication in less than 20 min, and longer treatment results in the formation of a homogeneous sol of HAp.

Type
Articles
Information
Journal of Materials Research , Volume 7 , Issue 8 , August 1992 , pp. 2294 - 2298
Copyright
Copyright © Materials Research Society 1992

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