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Designing a Delinked Incentive for Critical Antibiotics: Lessons from Norway

Published online by Cambridge University Press:  01 January 2021

Christine Årdal ,
Jostein Johnsen  and
Karianne Johansen
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Extract

No country has yet implemented a pilot to ensure access to or the innovation of new antibiotics for multi-drug infections. A team from national health agencies in Norway, with the support of the Innovative Medicine Initiative-funded project DRIVE-AB, designed a model suitable for the national context, including the selection of the antibiotics, the potential value, and the operational model.

Type
Symposium Articles
Information
Journal of Law, Medicine & Ethics , Volume 46 , Issue S1: Incentives to Stimulate Research and Development of New Antibiotics: Detailed Assessments of Select Incentives and Models , Spring 2018 , pp. 43 - 49
Copyright
Copyright © American Society of Law, Medicine and Ethics 2018

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References

Laxminarayan, R. et al., “Antibiotic Resistance: The Need for Global Solutions,” Lancet Infectious Diseases 13, no. 12 (2013): 1057–1098.Google Scholar
Holmes, A. H. et al., “Understanding the Mechanisms and Drivers of Antimicrobial Resistance,” The Lancet 387, no. 10014 (2016): 176–187.Google Scholar
Laxminarayan, R., “Antibiotic Effectiveness: Balancing Conservation against Innovation,” Science 345, no. 6202 (2014): 1299–1301.Google Scholar
Silver, L. L., “Challenges of Antibacterial Discovery,” Clinical Microbiology Reviews 24, no. 1 (2011): 71–109.CrossRefGoogle Scholar
Pew Charitable Trust, Antibiotics Currently in Clinical Development, available at <http://www.pewtrusts.org/en/multimedia/data-visualizations/2014/antibiotics-currently-in-clinical-development> (last visited October 6, 2017).+(last+visited+October+6,+2017).>Google Scholar
DRIVE-AB, Work Package 2, Task 3: Identified Risks and Bottlenecks to Antibiotics Innovation (2015), available at <http://drive-ab.eu/wp-content/uploads/2014/09/Report-Bottlenecks-and-risks-DRIVE-AB-Task-3-20151023-FINAL.pdf> (last visited January 11, 2018).+(last+visited+January+11,+2018).>Google Scholar
AMR Review, Tackling Drug-Resistant Infections Globally: Final Report and Recommendations (2016), available at <https://amr-review.org/sites/default/files/160525_Final%20paper_with%20cover.pdf> (last visited January 11, 2018)+(last+visited+January+11,+2018)>Google Scholar
Daniel, G. et al., “Addressing Antimicrobial Resistance and Stewardship: The Priority Antimicrobial Value and Entry (PAVE) Award,” JAMA 318, no. 12 (2017): 1103–1104.Google Scholar
The Boston Consulting Group, Breaking through the Wall: A Call for Concerted Action on Antibiotics Research and Development (2017), available at <http://www.bundesgesundheitsministerium.de/service/publikationen/gesundheit/details.html?bmg%5bpubid%5d=3006> (last visited January 11, 2018).+(last+visited+January+11,+2018).>Google Scholar
Folkhalsomyndigheten, Analys av förutsättningar för att testa en ny ersättningsmodell för antibiotika (2016), available at <https://www.folkhalsomyndigheten.se/publicerat-material/publikationsarkiv/a/analys-av-forutsattningar-for-att-testaen-ny-ersattningsmodell-for-antibiotika/> (last visited Jan. 11, 2018).+(last+visited+Jan.+11,+2018).>Google Scholar
Legemiddelforbruk.no, Drug Consumption in Norway, available at <http://www.legemiddelforbruk.no/> (last visited May 1, 2017).+(last+visited+May+1,+2017).>Google Scholar
Norwegian Competence Center for Antibiotic Use for Specialist Health Services, Nasjonal faglig retningslinje for bruk av antibiotika i sykehus, available at <https://helsedirektoratet.no/retningslinjer/antibiotika-i-sykehus> (last visited May 1, 2017).+(last+visited+May+1,+2017).>Google Scholar
Norwegian Medicines Agency, Find Medicine, available at <http://www.legemiddelverket.no> (last visited Dec. 1, 2017).+(last+visited+Dec.+1,+2017).>Google Scholar
Mosley, J. F. et al., “Ceftazidime-Avibactam (Avycaz): For the Treatment of Complicated Intra-Abdominal and Uri-nary Tract Infections,” Pharmacy and Therapeutics 41, no. 8 (2016): 479.Google Scholar
ECDC, Surveillance of Antimicrobial Consumption in Europe (2012), available at <https://ecdc.europa.eu/sites/portal/files/media/en/publications/Publications/antimicrobial-consumption-europe-esac-net-2012.pdf> (last visited Jan. 11, 2018).+(last+visited+Jan.+11,+2018).>Google Scholar
NORM/NORM-VET, Usage of Antimicrobial Agents and Occurrence of Antimicrobial Resistance in Norway (2015), available at <https://unn.no/Documents/Kompetansetjenester,%20-sentre%20og%20fagr%C3%A5d/NORM%20-%20Norsk%20overv%C3%A5kingssystem%20for%20anti-biotikaresistens%20hos%20mikrober/Rapporter/NORM_NORM-VET-2015.pdf> (last visited Jan. 11, 2018).+(last+visited+Jan.+11,+2018).>Google Scholar
Alberg, T. et al., “Antibiotikabruk og infeksjoner i sykehjem,” Tidsskr Nor Laegeforen 137, no. 6 (2017): 424.Google Scholar
Statens legemiddelverk, Legemiddelmangel og avregistre-ringer 2017: Råd til apotek og helsepersonell, available at <https://legemiddelverket.no/legemiddelmangel/legemiddelmangel-og-avregistreringer-2017-rad-til-apotek-og-helsepersonell> (last visited April 27, 2017).+(last+visited+April+27,+2017).>Google Scholar
ECDC, Rapid Risk Assessment: Carbapenem-Resistant Enterobacteriaceae (2016), available at <https://ecdc.europa.eu/sites/portal/files/media/en/publications/Publications/carbapenem-resistant-enterobacteriaceae-risk-assessment-april-2016.pdf> (last visited January 11, 2018).+(last+visited+January+11,+2018).>Google Scholar
Årdal, C. et al., DRIVE-AB Final Report - Revitalizing the Antibiotic Pipeline: Stimulating Innovation While Driving Sustainable Use and Global Access (2018), available at <http://www.imi.europa.eu/projects-results/project-fact-sheets/drive-ab> (last visited January 24, 2018)+(last+visited+January+24,+2018)>Google Scholar
Årdal, C. et al., “An Antibiotic's Journey from Marketing Authorization to Use, Norway,” Bulletin of the World Health Organization 95, no. 3 (2017): 220.CrossRefGoogle Scholar
Central Drugs Standard Control Organization, List of New Drug Approved from 01-01-2017 to Till Date by New Drugs Division, available at <http://cdsco.nic.in/forms/list.aspx?lid=2034&Id=11> (last visited May 8, 2017).+(last+visited+May+8,+2017).>Google Scholar
South African Medicine Price Registry, Database Of Medicine Prices 08th May 2017 (2017), available at <http://mpr.gov.za/PublishedDocuments.aspx> (last visited January 11, 2018).+(last+visited+January+11,+2018).>Google Scholar
The World Bank, Health Expenditure, Public (% of GDP), available at <http://data.worldbank.org/indicator/SH.XPD.PUBL.ZS> (last visited May 2, 2017).+(last+visited+May+2,+2017).>Google Scholar
Seya, M.-J. et al., “A First Comparison between the Consumption of and the Need for Opioid Analgesics at Country, Regional, and Global Levels,” Journal of Pain & Palliative Care Pharmacotherapy 25, no. 1 (2011): 6–18.CrossRefGoogle Scholar