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Sudden sensorineural hearing loss in a patient with primary antiphospholipid syndrome

Published online by Cambridge University Press:  10 April 2007

K-T Kang  and
Y-H Young
K-T Kang
Affiliation:
Department of Otolaryngology, National Taiwan University Hospital and National Taiwan University College of Medicine, Taipei, Taiwan
Y-H Young*
Affiliation:
Department of Otolaryngology, National Taiwan University Hospital and National Taiwan University College of Medicine, Taipei, Taiwan
*
Address for correspondence: Dr Yi-Ho Young, Department of Otolaryngology, National Taiwan University Hospital, 1 Chang-Te St, Taipei, Taiwan. Fax: +886 2 23946674 E-mail: [email protected]
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Abstract

Objective:

Despite multiple systemic manifestations, sudden sensorineural hearing loss in a patient with antiphospholipid syndrome is rarely reported.

Patient:

A 46-year-old man with primary antiphospholipid syndrome had a sudden onset of hearing loss and tinnitus in the right ear in December 2005, because he discontinued use of warfarin and acetylsalicylic acid for a few days.

Results:

Audiometry revealed saucer-type sensorineural hearing loss with a pure tone average of 73 dB in the right ear, and flat-type hearing loss with a pure tone average of 25 dB in the left ear. Electronystagmography displayed multiple central signs and bilateral canal paresis, while a vestibular evoked myogenic potential test revealed bilateral delayed responses. After admission, the patient was re-treated with warfarin and acetylsalicylic acid. Follow-up audiometry showed recovery of right-sided hearing, with a pure tone average of 12 dB, three days after presentation.

Conclusion:

Consensus exists on the effectiveness of anticoagulant agents in aiding a favourable outcome of sudden sensorineural hearing loss in patients with antiphospholipid syndrome.

Keywords

Antiphospholipid SyndromeSensorineural DeafnessWarfarin
Type
Clinical Records
Information
The Journal of Laryngology & Otology , Volume 122 , Issue 2 , February 2008 , pp. 204 - 206
Copyright
Copyright © JLO (1984) Limited 2007

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