Hostname: page-component-78c5997874-mlc7c Total loading time: 0 Render date: 2024-11-05T15:30:34.708Z Has data issue: false hasContentIssue false

Smooth muscle tumours of the larynx

Published online by Cambridge University Press:  29 June 2007

D. C. McKiernan
Affiliation:
Department of Otolaryngology, Radcliffe Infirmary, Woodstock Road, Oxford OX2 6HE.
G. W. R. Watters*
Affiliation:
Department of Otolaryngology, Radcliffe Infirmary, Woodstock Road, Oxford OX2 6HE.
*
Address for correspondence: Mr G. W. R. Watters, F.R.C.S., Department of Otolaryngology, Radcliffe Infirmary, Woodstock Road, Oxford OX2 6HE.

Abstract

Two cases of laryngeal smooth muscle tumours are reported: one a benign leiomyoma, the other a malignant leiomyosarcoma. These tumours may present diagnostic difficulties and immunocytochemistry is helpful in distinguishing smooth muscle tumours from other connective tissue neoplasms and spindle cell squamous carcinoma. Primary treatment in both cases should be surgical resection with small (T1, T2) malignant tumours suitable for partial laryngectomy. Postoperative radiotherapy may have a role in allowing a more limited surgical resection.

Type
Pathology in Focus
Copyright
Copyright © JLO (1984) Limited 1995

Access options

Get access to the full version of this content by using one of the access options below. (Log in options will check for institutional or personal access. Content may require purchase if you do not have access.)

References

Chen, J. M., Novick, W. H., Logan, C. A. (1991) Leiomyosarcoma of the larynx. Journal of Otolaryngology 20: 345348.Google ScholarPubMed
Fields, J. P., Helwig, E. B. (1981) Leiomyosarcoma of the skin and subcutaneous tissue. Cancer 47: 156169.3.0.CO;2-#>CrossRefGoogle ScholarPubMed
Frank, D. I. (1941) Leiomyosarcoma of the larynx. Archives of Otolaryngology 34: 493500.CrossRefGoogle Scholar
Fu, Y. S., Perzin, K. H. (1975) Nonepithelial tumours of the nasal cavity, paranasal sinuses, and nasopharynx: a clinicopathologic study. IV: Smooth muscle tumours (leiomyoma, leiomyosarcoma). Cancer 35: 13001308.3.0.CO;2-Z>CrossRefGoogle ScholarPubMed
Goldberg, S. H., Hanft, K., Ossakow, S. J. (1988) Residents page. Pathologic quiz: Case 1. Archives of Otolaryngology, Head and Neck Surgery 114: 13301332.Google Scholar
Hellquist, H. B., Hellqvist, H., Vejlens, L., Lindholm, C. E. (1994) Epithelioid leiomyoma of the larynx. Histopathology 24: 155159.CrossRefGoogle ScholarPubMed
Josephson, R. L., Blair, R. L., Bedard, Y. C. (1985) Leiomyosarcoma of the nose and paranasal sinuses. Otolaryngology-Head and Neck Surgery 93: 270274.CrossRefGoogle ScholarPubMed
Kahn, J., Korol, H. (1989) Residents page. Pathologic quiz: Case 2. Archives of Otolaryngology, Head and Neck Surgery 115: 114117.Google Scholar
Karma, P., Hyrynkangas, K., Rasenan, O. (1978) Laryngeal leiomyoma. Journal of Laryngology and Otology 92: 411415.CrossRefGoogle ScholarPubMed
Kaya, S., Levent, S., Sevket, R. (1990) Laryngeal leiomyoma. International Journal of Pediatric Otorhinolaryngology 19: 285288.CrossRefGoogle ScholarPubMed
Kleinsasser, O., Glanz, H. (1979) Myogenic tumours of the larynx. Archives of Otorhinolaryngology 225: 107119.CrossRefGoogle ScholarPubMed
Kuruvilla, A., Wenig, B. M., Humphrey, D. M., Heffner, D. K. (1990) Leiomyosarcoma of the sinonasal tract. Archives of Otolaryngology, Head and Neck Surgery 116: 12781286.CrossRefGoogle ScholarPubMed
Michaels, L. (1987) Ear, Nose and Throat Histopathology. Springer-Verlag, Berlin, p 443.CrossRefGoogle Scholar
Mindell, R. S., Calcaterra, T. C, Ward, P. H. (1975) Leiomyosarcoma of the head and neck. Laryngoscope 85: 904910.CrossRefGoogle ScholarPubMed
Naresh, K. N., Pai, S. A., Vyas, j. J., Soman, C. S. (1993) Leiomyoma of the bronchus: a case report. Histopathology 22: 288289.CrossRefGoogle ScholarPubMed
Rowe-Jones, J. M., Solomons, N. B., Ratcliffe, N. A. (1994) Leiomyosarcoma of the larynx. Journal of Laryngology and Otology 108: 359362.CrossRefGoogle ScholarPubMed
Tewary, A. K., Pahor, A. L. (1991) Leiomyosarcoma of the larynx: emergency laryngectomy. Journal of Laryngology and Otology 105: 134136.CrossRefGoogle ScholarPubMed
Wile, A. G., Evans, H. L., Romsdal, M. M. (1981) Leiomyosarcoma of soft tissue: a clinicopathologic study. Cancer 48: 10221032.3.0.CO;2-5>CrossRefGoogle Scholar