Hostname: page-component-586b7cd67f-rcrh6 Total loading time: 0 Render date: 2024-11-26T22:47:55.969Z Has data issue: false hasContentIssue false
  • English
  • Français

Correlation between radiological images and pathological results in supraglottic cancer

Published online by Cambridge University Press:  03 March 2008

J W Kim ,
S-Y Yoon ,
I-S Park ,
S-W Park  and
Y-M Kim
J W Kim
Affiliation:
Department of Otorhinolaryngology, Inha University, College of Medicine, Incheon, South Korea
S-Y Yoon
Affiliation:
Department of Otorhinolaryngology, Inha University, College of Medicine, Incheon, South Korea
I-S Park
Affiliation:
Department of Pathology, Inha University, College of Medicine, Incheon, South Korea
S-W Park
Affiliation:
Department of Radiology, Inha University, College of Medicine, Incheon, South Korea
Y-M Kim*
Affiliation:
Department of Otorhinolaryngology, Inha University, College of Medicine, Incheon, South Korea
*
Address for correspondence: Dr Young-Mo Kim, Department of Otorhinolaryngology-Head and Neck Surgery, Inha University College of Medicine, 3-Ga Shinheung-dong, Jung-Gu, Incheon 400-711, South Korea. Fax: 82-32-890-3580 E-mail: [email protected]
Get access Rights & Permissions [Opens in a new window]

Abstract

Introduction:

Radiological imaging plays an indispensable, complementary role to endoscopy in the pre-therapeutic assessment of laryngeal cancer. We evaluated the reliability of radiological imaging in determining the extent of cancer and surgical resection, by comparing the results of pre-operative computed tomography and magnetic resonance imaging with those for post-operative pathological analysis.

Material and methods:

Twenty-nine patients who had undergone laryngeal cancer surgery with a diagnosis of supraglottic cancer were reviewed. Imaging reliability was assessed for separate subunit regions of the supraglottic area, the glottic area and the cartilage.

Results:

The false diagnosis rate for all subunits was 25 per cent. The rate of false diagnosis associated with overstaging was 21 per cent. The rate of false diagnosis associated with understaging was 4 per cent.

Conclusion:

In order to give the best chance of laryngeal preservation, especially in the case of false positive laryngeal subsites, computed tomography and magnetic resonance imaging should be combined with pre-operative endoscopy and intra-operative frozen section diagnosis.

Keywords

Larynx NeoplasmsComputed TomographyMagnetic Resonance ImagingNeoplasm Staging
Type
Main Articles
Information
The Journal of Laryngology & Otology , Volume 122 , Issue 11 , November 2008 , pp. 1224 - 1229
Copyright
Copyright © JLO (1984) Limited 2008

Access options

Get access to the full version of this content by using one of the access options below. (Log in options will check for institutional or personal access. Content may require purchase if you do not have access.)

References

1 Mendenhall, WM, Werning, JW, Hinerman, RW, Amdur, RJ, Villaret, DB. Management of T1-T2 glottic carcinomas. Cancer 2004;100:1786–92Google Scholar
2 Agada, FO, Nix, PA, Salvage, D, Stafford, ND. Computerised tomography vs. pathological staging of laryngeal cancer: a 6-year completed audit cycle. Int J Clin Pract 2004;58:714–16Google Scholar
3 Buckley, JG, MacLennan, K. Cancer spread in the larynx: a pathologic basis for conservation surgery. Head Neck 2000;22:265–74Google Scholar
4 Phelps, PD. Carcinoma of the larynx – the role of imaging in staging and pre-treatment assessments. Clin Radiol 1992;46:77–83Google Scholar
5 Kwan-Moon, Kim, Young-Ho, Kim, Jung Il, Cho, Myung Sang, Kim, Sung Soo, Park, Sang Kyun, Kim et al. The correlation between CT, MR image and whole organ section in the cancerous larynges. Korean Journal of Otolaryngology 1995;38:739–45Google Scholar
6 Mafee, MF, Schild, JA, Michael, AS, Choi, KH, Capek, V. Cartilage involvement in laryngeal carcinoma: correlation of CT and pathologic macrosection studies. J Comput Assist Tomogr 1984;8:969–73CrossRefGoogle ScholarPubMed
7 Castelijns, JA, Doornbos, J, Verbeeten, B Jr, Vielvoye, GJ, Bloem, JL. MR image of the normal larynx. J Comput Assist Tomogr 1985;9:919–25Google Scholar
8 Nix, PA, Salvage, D. Neoplastic invasion of laryngeal cartilage: the significance of cartilage sclerosis on computed tomography images. Clin Otolaryngol Allied Sci 2004;29:372–5Google Scholar
9 Becker, M, Zbaren, P, Delavelle, J, Kurt, AM, Egger, C, Rufenacht, DA et al. Neoplastic invasion of the laryngeal cartilage: reassessment of criteria for diagnosis at CT. Radiology 1997;203:521–32CrossRefGoogle ScholarPubMed
10 Becker, M, Zbaren, P, Laeng, H, Stoupis, C, Porcellini, B, Vock, P. Neoplastic invasion of the laryngeal cartilage: comparison of MR imaging and CT with histopathologic correlation. Radiology 1995;194:661–9Google Scholar
11 Zbären, P, Becker, M, Laeng, H. Pretherapeutic staging of laryngeal cancer: clinical findings, computed tomography and magnetic resonance imaging versus histopathology. Cancer 1996;77:1263–73Google Scholar
12 Loevner, LA, Yousem, DM, Montone, KT, Weber, R, Chalian, AA, Weinstein, GS. Can radiologists accurately predict preepiglottic space invasion with MR imaging? AJR Am J Roentgenol 1997;169:1681–7Google Scholar
13 Korkmaz, H, Cerezci, NG, Akmansu, H, Dursun, E. A comparison of spiral and conventional computerized tomography methods in diagnosing various laryngeal lesions. Eur Arch Otorhinolaryngol 1998;255:149–54Google Scholar