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Wegener's granulomatosis presenting as major salivary gland enlargement

Published online by Cambridge University Press:  29 June 2007

K. W. Ah-See ,
K. McLaren  and
A. G. D. Maran
K. W. Ah-See*
Affiliation:
Department of Otolaryngology, City Hospital, Edinburgh, UK.
K. McLaren
Affiliation:
Department of Pathology, University of Edinburgh, Edinburgh, UK.
A. G. D. Maran
Affiliation:
Department of Otolaryngology, City Hospital, Edinburgh, UK.
*
Address for correspondence: Dr K. W. Ah-See, Department of ENT, City Hospital, Greenbank Drive, Edinburgh EH10 5SB. Fax: 0131-536-6167
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Abstract

Salivary gland involvement is rare in Wegener's granulomatosis. We report the first case of widespread major salivary gland enlargement as part of the presentation of this disease. A review of the few reported cases in the literature suggests that salivary gland involvement may be associated with a limited form of the disease and an improved prognosis. The anti-neutrophil cytoplasmic antibody (c-ANCA) assay remains the gold standard of diagnosis but care should be exercised in the interpretation of results. This patient responded well to current immunosuppressive therapy.

Keywords

Wegener's granulomatosisParotid glandSubmandibular gland
Type
Clinical Records
Information
The Journal of Laryngology & Otology , Volume 110 , Issue 7 , July 1996 , pp. 691 - 693
Copyright
Copyright © JLO (1984) Limited 1996

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