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Strongyloides ratti: dissociation of immunological memory of the protection against tissue migrating larvae and intestinal adult worms in mice

Published online by Cambridge University Press:  05 June 2009

T. Abe ,
K. Yoshimura  and
Y. Nawa
T. Abe
Affiliation:
Department of Parasitology, Akita University School of Medicine, Hondo, Akita 010
K. Yoshimura
Affiliation:
Department of Parasitology, Akita University School of Medicine, Hondo, Akita 010
Y. Nawa
Affiliation:
Department of Parasitology, Miyazaki Medical College, Kiyotake, Miyazaki 889–16, Japan
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Abstract

Immunological memory generated by infection with S. ratti was studied separately in the migratory and intestinal phases in mice. Protection against reinfection in the migratory phase was 96–98% at 2 weeks but significantly decreased to 60% at 12 weeks after the primary infection. However, protection in the intestinal phase was 96% even 12 weeks after the primary infection. Recall of immunity against the intestinal phase persists for longer than that against the migratory phase in mice.

Keywords

Strongyloides rattiprotectionmemorymigratory phaseintestinal phasemiceNematodaimmunology
Type
Research Note
Information
Journal of Helminthology , Volume 67 , Issue 2 , June 1993 , pp. 161 - 164
Copyright
Copyright © Cambridge University Press 1993

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References

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