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Repeated antigen testing among severe acute respiratory coronavirus virus 2 (SARS-CoV-2)–positive nursing home residents

Part of: SARS-CoV-2/COVID-19

Published online by Cambridge University Press:  20 August 2021

Erin D. Moritz Open the ORCID record for Erin D. Moritz [Opens in a new window] ,
Susannah L. McKay ,
Farrell A. Tobolowsky ,
Stephen P. LaVoie ,
Michelle A. Waltenburg ,
Kristin D. Lecy ,
Natalie J. Thornburg ,
Jennifer L. Harcourt ,
Azaibi Tamin  and
Jennifer M. Folster
...Show all authors
Erin D. Moritz*
Affiliation:
COVID-19 Response Team, Centers for Disease Control and Prevention, Atlanta, Georgia
Susannah L. McKay
Affiliation:
COVID-19 Response Team, Centers for Disease Control and Prevention, Atlanta, Georgia
Farrell A. Tobolowsky
Affiliation:
COVID-19 Response Team, Centers for Disease Control and Prevention, Atlanta, Georgia
Stephen P. LaVoie
Affiliation:
COVID-19 Response Team, Centers for Disease Control and Prevention, Atlanta, Georgia
Michelle A. Waltenburg
Affiliation:
COVID-19 Response Team, Centers for Disease Control and Prevention, Atlanta, Georgia
Kristin D. Lecy
Affiliation:
COVID-19 Response Team, Centers for Disease Control and Prevention, Atlanta, Georgia
Natalie J. Thornburg
Affiliation:
COVID-19 Response Team, Centers for Disease Control and Prevention, Atlanta, Georgia
Jennifer L. Harcourt
Affiliation:
COVID-19 Response Team, Centers for Disease Control and Prevention, Atlanta, Georgia
Azaibi Tamin
Affiliation:
COVID-19 Response Team, Centers for Disease Control and Prevention, Atlanta, Georgia
Jennifer M. Folster
Affiliation:
COVID-19 Response Team, Centers for Disease Control and Prevention, Atlanta, Georgia
Jeanne Negley
Affiliation:
Acute Disease Epidemiology, Georgia Department of Public Health, Atlanta, Georgia
Allison C. Brown
Affiliation:
COVID-19 Response Team, Centers for Disease Control and Prevention, Atlanta, Georgia
L. Clifford McDonald
Affiliation:
COVID-19 Response Team, Centers for Disease Control and Prevention, Atlanta, Georgia
Preeta K. Kutty
Affiliation:
COVID-19 Response Team, Centers for Disease Control and Prevention, Atlanta, Georgia
*
Author for correspondence: Erin D. Moritz, E-mail: [email protected]
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Abstract

Repeated antigen testing of 12 severe acute respiratory coronavirus virus 2 (SARS-CoV-2)–positive nursing home residents using Abbott BinaxNOW identified 9 of 9 (100%) culture-positive specimens up to 6 days after initial positive test. Antigen positivity lasted 2–24 days. Antigen positivity might last beyond the infectious period, but it was reliable in residents with evidence of early infection.

Type
Concise Communication
Information
Infection Control & Hospital Epidemiology , Volume 43 , Issue 12 , December 2022 , pp. 1918 - 1921
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Copyright
© The Author(s), 2021. Published by Cambridge University Press on behalf of The Society for Healthcare Epidemiology of America

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Footnotes

a

CDC Infection Prevention and Control Group: Amelia Bhatnagar BS1, Malania M. Wilson MS1, Kelly M. Hatfield MSPH1, Sarah E. Gilbert MPH1, James L. Dawson PhD1, Jonathan Bryant-Genevier PhD1, Matthew J. Hudson MD1, Geroncio C. Fajardo MD1, David A. Jackson MD1, Laura G. Brown PhD1, Juliana Carvalho DaSilva MA1 and Melia Haile MPH.1

References

COVID-19 in nursing homes. US Government Accountability Office website. https://www.gao.gov/assets/gao-21-367.pdf. Published 2021. Accessed May 27, 2021.Google Scholar
Nursing home data—point of care device allocation. Centers for Medicare and Medicaid Services website. https://data.cms.gov/Special-Programs-Initiatives-COVID-19-Nursing-Home/Nursing-Home-Data-Point-of-Care-Device-Allocation/jbvf-tb74. Published 2020. Accessed January 27, 2021.Google Scholar
Interim guidance for antigen testing for SARS-CoV-2. Centers for Disease Control and Prevention website. https://www.cdc.gov/coronavirus/2019-ncov/lab/resources/antigen-tests-guidelines.html. Published 2021. Accessed May 27, 2021.Google Scholar
SARS-CoV-2 antigen testing in long-term care facilities. Centers for Disease Control and Prevention website. https://www.cdc.gov/coronavirus/2019-ncov/hcp/nursing-homes-antigen-testing.html. Published 2021. Accessed May 27, 2021.Google Scholar
BinaxNOW COVID-19 Ag Card—instructions for use. US Food and Drug Administration website. https://www.fda.gov/media/141570/download. Published 2020. Accessed January 27, 2021.Google Scholar
McKay, SL, Tobolowsky, FA, Moritz, ED, et al. Performance evaluation of serial SARS-CoV-2 rapid antigen testing during a nursing home outbreak. Ann Intern Med 2021. doi: 10.7326/M21-0422.Google Scholar
Protection of human subjects. 45 C.F.R. part 46.102(l)(2). Code of Federal Regulations. 2018.Google Scholar
Institutional review boards. 21 C.F.R. part 56. Code of Federal Regulations. 1981.Google Scholar
Records maintained on individuals. 5 U.S.C. §552a. United States Code. 2018.Google Scholar
Purposes. 44 U.S.C. §3501. United States Code. 2018.Google Scholar
Research and investigations generally. 42 U.S.C. §241(d). United States Code. 2011.Google Scholar
Surie, D, Huang, JY, Brown, AC, et al. Infectious period of severe acute respiratory syndrome coronavirus 2 in 17 nursing home residents—Arkansas, June–August 2020. Open Forum Infect Dis 2021. doi: 10.1093/ofid/ofab048.Google Scholar
Hirotsu, Y, Maejima, M, Shibusawa, M, et al. Comparison of automated SARS-CoV-2 antigen test for COVID-19 infection with quantitative RT-PCR using 313 nasopharyngeal swabs, including from seven serially followed patients. Int J Infect Dis 2020;99:397–402.CrossRefGoogle ScholarPubMed