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Screening for a false unipolarity in patients treated for a major depressive disorder

Published online by Cambridge University Press:  13 August 2021

N. Regaieg ,
I. Baati ,
F. Ben Amor ,
M. Kallel ,
S. Hentati  and
J. Masmoudi
N. Regaieg*
Affiliation:
Psychiatry “a” Department, Hedi Chaker UHC, Sfax, Tunisia
I. Baati
Affiliation:
Psychiatry “a” Department, Hedi Chaker University Hospital, Sfax, Tunisia
F. Ben Amor
Affiliation:
Psychiatry “a” Department, Hedi Chaker University Hospital, Sfax, Tunisia
M. Kallel
Affiliation:
Psychiatry “a” Department, Hedi Chaker UHC, Sfax, Tunisia
S. Hentati
Affiliation:
Psychiatry “a” Department, Hedi Chaker University Hospital, Sfax, Tunisia
J. Masmoudi
Affiliation:
Psychiatrie “a” Department, Hedi Chaker Hospital University -Sfax - Tunisia, sfax, Tunisia
*
*Corresponding author.

Abstract

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Introduction

The early diagnosis of bipolar II disorder remains difficult in clinical practice, hence the importance of psychometric tests.

Objectives

To detect hypomania in patients followed for a major depressive disorder (MDD) and to determine factors which are correlated with it.

Methods

This was a cross-sectional, descriptive and analytical study. It involved 40 psychiatric outpatients, who were followed for MDD (isolated or recurrent episode) at the Hedi Chaker University Hospital in Sfax (Tunisia), from January 26 to February 10, 2020. The study was conducted using a questionnaire and the Angst Hypomania Checklist-20 (HCL-20).

Results

The sex ratio (M/F) was 0.66 with an average age of 54.8 years. MDD started at an average age of 41.45 years. According to HCL-20, half of our sample had hypomania. The presence of hypomania was correlated with young age (p = 0.022), academic failure (p = 0.038) and smoking (p = 0.003). In addition, there was a statistically significant relationship between the presence of hypomania and the characteristics of the disease: number of depressive episodes ≥ 2 (p = 0.013), psychotic features (p = 0.038), melancholic features (p=0,025) and premature discontinuation of treatment (p = 0.003).

Conclusions

Our study confirmed that bipolar depression is still underdiagnosed and poorly treated. Questioning a patient about a history of hypomania would be a delicate task and would require the help of a scale, in particular the HCL -20.

Keywords

HCL-20bipolar depressionbipolar II disorderhypomania
Type
Abstract
Information
European Psychiatry , Volume 64 , Special Issue S1: Abstracts of the 29th European Congress of Psychiatry , April 2021 , pp. S200 - S201
Creative Commons
Creative Common License - CCCreative Common License - BY
This is an Open Access article, distributed under the terms of the Creative Commons Attribution licence (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted re-use, distribution, and reproduction in any medium, provided the original work is properly cited.
Copyright
© The Author(s), 2021. Published by Cambridge University Press on behalf of the European Psychiatric Association
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