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P03-329 - Impact of Transition to Atypical Antipsychotics in the Course and Outcome of First-time Admittances in a Psychiatric Clinic

Published online by Cambridge University Press:  17 April 2020

G. Floros
Affiliation:
2nd Department of Psychiatry, Aristotles University of Thessaloniki, Thessaloníki, Greece
I. Grammatikopoulos
Affiliation:
2nd Department of Psychiatry, Aristotles University of Thessaloniki, Thessaloníki, Greece
M. Girouki
Affiliation:
2nd Department of Psychiatry, Aristotles University of Thessaloniki, Thessaloníki, Greece
V. Amanatiadis
Affiliation:
2nd Department of Psychiatry, Aristotles University of Thessaloniki, Thessaloníki, Greece
E. Ntouros
Affiliation:
2nd Department of Psychiatry, Aristotles University of Thessaloniki, Thessaloníki, Greece
G. Pahumis
Affiliation:
2nd Department of Psychiatry, Aristotles University of Thessaloniki, Thessaloníki, Greece
N. Nikolaidis
Affiliation:
2nd Department of Psychiatry, Aristotles University of Thessaloniki, Thessaloníki, Greece
G. Garyfallos
Affiliation:
2nd Department of Psychiatry, Aristotles University of Thessaloniki, Thessaloníki, Greece
I. Giouzepas
Affiliation:
2nd Department of Psychiatry, Aristotles University of Thessaloniki, Thessaloníki, Greece

Abstract

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Objectives

We examined the course of patients admitted for the first time in the Acute mental health ward of a Psychiatric Clinic in a Psychiatric Hospital within a ten-year hiatus. During this time the sociodemographic characteristics of the population were altered due to migration from former Eastern Europe countries, the transition from typical to atypical antipsychotic medication was completed and attempts were made to promote community psychiatry.

Methods

We compared two groups of 77 and 87 patients admitted for the first time during 1997 and 2007 respectively. Prescribed medication when given an exit diagnosis was calculated to haloperidol equivalency, following guidelines described in Kane et al.

Results

Results indicate that the groups were comparable as to size, sex, age, entry diagnosis and length of stay. The groups differed significantly as to origin, with the 2007 group having significantly more migrants but also patients originating from more distant provinces within Greece. There was a significant increase in involuntary admissions. While there was an increase in the use of atypical antipsychotics there was no significant difference in treatment potency.

Conclusions

Introduction of atypical antipsychotics enabled the clinician to provide treatment of similar antipsychotic potency with better tolerance profile, but failed to reduce length of stay. The increase in involuntary admissions and number of admissions from more remote regions raises doubts on the efficiency of the psychiatric reforms attempted during that time in order to promote community psychiatry.

Type
Psychopharmacological treatment and biological therapies
Copyright
Copyright © European Psychiatric Association 2010

References

Kane., , et al.Expert consensus guidelines for optimizing pharmacologic treatment of psychotic disorders. JClinPsychiatry 2003; 64(12): 519Google ScholarPubMed
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