The relationship between selective serotonin reuptake inhibitors(SSRI`S) is presented.

The SSRI dependent side effects are mostly characterized by serotonin potentiation.

Both SSRI`S and tricyclic antidepressants can also cause extrapyramidal side effects.

The occurence of movement disorders such as akathisia, dystonia and Parkinsonism after use of SSRI`S was reported.

Furthermore descriptions of deterioration of Parkinson`s disease after use of fluoxetine, fluvoxamine and paroxetine can be found in the literature.

Medication having a serotonergic effect can cause a prolactin level elevation through an indirect mechanism.

Prolactine elevation may cause galactorrhea.

Two mechanism are considered to explain the prolactin release induced by the serotonergic system: the presynaptic inhibition of dopamine discharge by the serotonergic receptors or the direct stimulation of the hypothalamic postsynaptic receptors.