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Oxcarbazepine as a mood stabiliser.
Published online by Cambridge University Press: 16 April 2020
Abstract
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Carbamazepine as a mood stabiliser: A well-known mood stabiliser. Oxcarbazepine is a metabolite of carbamazepine and works as an anti-epileptic, but it has a more favourable pharmacological profile. Researchers have been studying its mood stabilising effect in bipolar disorders for decades. We have carried out a retrospective study of 7 patient charts.
Results:
7 women; average age: 44 years old; onset of bipolar disorder at the age of 32.
Continous use of oxcarbazepine: 26.1 months and continuous use of the previous mood stabiliser: 20.6 months. The percentage of time spent in euthymia improved from an average of 48% with the previous mood stabiliser to 62% with oxcarbazepine. The percentage of time spent ill both of (hypo)mania and of depression decreased respectively from 24% to 18% and from 25% to 19% with the use of oxcarbazepine. Improvement occurred with 4 of the 7 patients.
Conclusion:
These results are in accordance with the literature. Oxcarbazepine has the advantage of fewer (drug-to drug) interactions than carbamazepine.
- Type
- Poster Session 2: Bipolar Disorders
- Information
- European Psychiatry , Volume 22 , Issue S1: 15th AEP Congress - Abstract book - 15th AEP Congress , March 2007 , pp. S261
- Copyright
- Copyright © European Psychiatric Association 2007
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