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Neuroleptics and cancer

Published online by Cambridge University Press:  16 April 2020

G.J. Gómez-Bernal
Affiliation:
Hospital Psiquiátrico de Teruel, Spain
A. Reboreda
Affiliation:
Hospital Psiquiátrico de Teruel, Spain
M. Bernal
Affiliation:
Universidad de Zaragoza, Zaragoza, Spain
F. Romero
Affiliation:
Hospital Psiquiátrico de Teruel, Spain
E. Esteban
Affiliation:
Hospital Psiquiátrico de Teruel, Spain

Abstract

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Background and aims:

There are some indications in the literature that the use of dopamine antagonists can modify the risk of developing different types of neoplasms.

Methods:

We have reviewed last studies which have reported the possible relationship between cancer and neuroleptic treatment.

Results and Conclusions:

Antipsychotics which increase the level of prolactin, could possible increase the risk of developing breast and endometrial cancer in patients with schizophrenia. Other studies, shows a marked apoptotic effect of phenothiazines in brain-derived cancer cells.

Type
Poster Session 1: Antipsychotic Medications
Copyright
Copyright © European Psychiatric Association 2007
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