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Factors influencing quality of life and well being in metastatic prostate cancer patients

Published online by Cambridge University Press:  19 July 2023

K. Bouassida ,
A. Loghmari ,
M. Ben Othmen ,
G. Tlili ,
E. Acacha ,
W. Ben Abdallah ,
M. Kahloul ,
W. Hmida  and
M. Jaidane
K. Bouassida
Affiliation:
Urology
A. Loghmari*
Affiliation:
Urology
M. Ben Othmen
Affiliation:
Urology
G. Tlili
Affiliation:
Urology
E. Acacha
Affiliation:
Urology
W. Ben Abdallah
Affiliation:
Urology
M. Kahloul
Affiliation:
Anesthesiology department, Sahloul teachin Hospital Sousse, Sousse, Tunisia
W. Hmida
Affiliation:
Urology
M. Jaidane
Affiliation:
Urology
*
*Corresponding author.

Abstract

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Introduction

Improving health-related quality of life (HRQL) is the main goal of palliative care. It requires consensual management strategies and specific measures targeting modifiable factors that could affect the quality of life.

Objectives

The aim of this study was to identify factors influencing the quality of life of patients with metastatic prostate cancer in a limited resources country.

Methods

This is a retrospective and analytical study enrolling all patients with metastatic prostate cancer who were managed at medical oncology and urology consultations of two Tunisian teaching hospital. HRQL was measured using UCLA prostate cancer index and SF-36 SCALE. The influence of demographic and medical characteristics on HRQL was determined using t tests and analysis of variance, with Tukey’s correction for multiple comparisons.

Multivariate linear regression was used to determine independent predictor

Results

This study enrolled 244 patients. The mean age was 72 years. The strongest determinants of overall HRQL after univariate analysis were: increased age (p = 0.006), lower income (p = 0.009), sexual function problems (p = 0.004), urinary function problems (p = 0.002) and symptoms such as pain (p = 0.001) and asthenia (p = 0.001).

Conclusions

Age, income, sexual and urinary functions are important determinants of HRQL in patients with metastatic prostate cancer that may require specific interventions.

Disclosure of Interest

None Declared

Type
Abstract
Information
European Psychiatry , Volume 66 , Special Issue S1: Abstracts of the 31st European Congress of Psychiatry , March 2023 , pp. S943 - S944
Creative Commons
Creative Common License - CCCreative Common License - BY
This is an Open Access article, distributed under the terms of the Creative Commons Attribution licence (https://creativecommons.org/licenses/by/4.0/), which permits unrestricted re-use, distribution, and reproduction in any medium, provided the original work is properly cited.
Copyright
© The Author(s), 2023. Published by Cambridge University Press on behalf of the European Psychiatric Association
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