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Basic symptoms as subjective cognitive deficit in schizophrenia: Cognitive, clinical and functional associations

Published online by Cambridge University Press:  23 March 2020

M.L. Vargas ,
S. López-Lorenzo ,
I. Legascue ,
A. Nagore ,
P. Serrano  and
N. Jimeno-Bulnes
M.L. Vargas*
Affiliation:
Complejo Asistencial de Segovia, Grupo de Investigación en Neurociencia Clínica de Segovia GINCS, Psychiatry, Segovia, Spain
S. López-Lorenzo
Affiliation:
Grupo de Investigación en Neurociencia Clínica de Segovia GINCS, Psychiatry, Segovia, Spain
I. Legascue
Affiliation:
Grupo de Investigación en Neurociencia Clínica de Segovia GINCS, Psychiatry, Segovia, Spain
A. Nagore
Affiliation:
Grupo de Investigación en Neurociencia Clínica de Segovia GINCS, Psychiatry, Segovia, Spain
P. Serrano
Affiliation:
Grupo de Investigación en Neurociencia Clínica de Segovia GINCS, Psychiatry, Segovia, Spain
N. Jimeno-Bulnes
Affiliation:
Universidad de Valladolid, Grupo de Investigación en Neurociencia Clínica de Segovia GINCS, Psychiatry, Segovia, Spain
*
* Corresponding author.

Abstract

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Introduction

Basic symptoms are subjective complaints that present at the early states in psychotic disorders and persist in the long-term. They can be studied using hetero applied clinical instruments or self-administered questionnaires. Basic symptoms can be useful as screening tools in at risk populations.

Aims

To determine if basic symptoms (subjective cognitive deficits) are associated with the objectively measured cognitive deficit after controlling for functioning and symptomatology.

Methods

One observational, transversal, psychopathological and neuropsychological study was performed on a schizophrenia outpatients sample (n = 78). Correlations were measured by using Spearman's Rho coefficient. Basic symptoms were registered by using the Frankfurt Complaints Questionnaire (FCQ-3); cognitive status was assessed by Repeatable Battery for the Assessment of Neuropsychological Status (RBANS); clinical status was assessed by PANSS and Clinical Global Impression (CGI); functional status was measured with Global Assessment of Functioning (GAF).

Results

All the dimensions were related to subjective complaints: cognitive functioning (r = −.38; P < .001); positive symptoms (r = .54; P < .001); negative symptoms (r = .26; P < .02); general symptoms (r = .41; P < .001); CGI (r = .57; P < .001); GAF (r = −.45; P < .001). The association between subjective and objective cognitive deficit remains significative after controlling for the clinical and functional variables, except when controlling for CGI.

Conclusions

The evaluation of basic symptoms with FCQ-3 is related with an objective cognitive deficit and could be useful as a screening tool.

Disclosure of interest

The authors have not supplied their declaration of competing interest.

Type
FC93
Information
European Psychiatry , Volume 33 , Issue S1: Abstracts of the 24th European Congress of Psychiatry , March 2016 , pp. S108
Copyright
Copyright © European Psychiatric Association 2016
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