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832 – Predictors of Outcome of Complex In-patient Therapeutic Program for Pharmacoresitant Obsessive Compulsive Patients

Published online by Cambridge University Press:  15 April 2020

M. Cerna ,
J. Prasko ,
A. Grambal ,
D. Jelenova ,
D. Kamaradova ,
K. Latalova ,
M. Ociskova  and
Z. Sedlackova
M. Cerna
Affiliation:
Department of Psychiatry, Faculty of Medicine and Dentistry, University Palacky Olomouc, University Hospital Olomouc
J. Prasko
Affiliation:
Department of Psychiatry, Faculty of Medicine and Dentistry, University Palacky Olomouc, University Hospital Olomouc
A. Grambal
Affiliation:
Department of Psychiatry, Faculty of Medicine and Dentistry, University Palacky Olomouc, University Hospital Olomouc
D. Jelenova
Affiliation:
Department of Psychiatry, Faculty of Medicine and Dentistry, University Palacky Olomouc, University Hospital Olomouc
D. Kamaradova
Affiliation:
Department of Psychiatry, Faculty of Medicine and Dentistry, University Palacky Olomouc, University Hospital Olomouc
K. Latalova
Affiliation:
Department of Psychiatry, Faculty of Medicine and Dentistry, University Palacky Olomouc, University Hospital Olomouc
M. Ociskova
Affiliation:
Department of Psychology, Philosophical Faculty, University Palacky Olomouc, Olomouc, Czech Republic
Z. Sedlackova
Affiliation:
Department of Psychology, Philosophical Faculty, University Palacky Olomouc, Olomouc, Czech Republic

Abstract

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The aim of the study was to assess the efficacy of the in-patients therapeutic program for in patients suffering with pharmacoresistant OCD patients. the therapy was conducted in a group setting and systematic CBT steps were adapted to each individual patient in the group. Pharmacological treatment underwent no or minimal changes during the trial period. Outcome measures included the Yale-Brown Obsessive Compulsive Scale, subjective version (S-Y-BOCS), the Clinical Global Impressions-Severity of Illness scale (CGI-S), Beck Depression Inventory (BDI), Beck Anxiety Inventory (BAI), and Dissociative Experience Scale (DES). the primary outcome measure for treatment response was a rating of 35% improvement in Y-BOCS. A remission was defined by S-Y-BOCS score 12 and lower or by CGI-S scores 1 or 2.

Results:

66 patients completed trial. Three patients refused the protocol. All patients finished minimum of 6 weeks of CBT and showed statistically significant improvement on S-Y-BOCS, CGI-S and BDI scales. the main predictors of achieving the response or remission were scores in S-Y-BOCS lower than 24, good insight, high resistance against symptoms, low level of dissociation, and aggressive character of obsessions. the negative predictors of achieving the response or remission were control/symmetry obsession and compulsions, and obsessive slowness/ambivalence.

Supported by:

IGA MZ CR NT 11047-4/2010

Type
Abstract
Information
European Psychiatry , Volume 28 , Issue S1: Abstracts of the 21th European Congress of Psychiatry , 2013 , 28-E294
Copyright
Copyright © European Psychiatric Association 2013
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