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1453 – Depression And Methadone Maintenance Treatment

Published online by Cambridge University Press:  15 April 2020

M. Andrijevic ,
M. Paunovic Manic ,
K. Seslija ,
S. Bivolarevic  and
M. Miskovic
M. Andrijevic
Affiliation:
Methadone Center, Primary Health Care Center Savski Venac, Belgrade, Serbia
M. Paunovic Manic
Affiliation:
Methadone Center, Primary Health Care Center Savski Venac, Belgrade, Serbia
K. Seslija
Affiliation:
Methadone Center, Primary Health Care Center Savski Venac, Belgrade, Serbia
S. Bivolarevic
Affiliation:
Methadone Center, Primary Health Care Center Savski Venac, Belgrade, Serbia
M. Miskovic
Affiliation:
Methadone Center, Primary Health Care Center Savski Venac, Belgrade, Serbia

Abstract

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Aims

Study followed appearance and treatment of depressive disorder at the patients with opiates dependency on methadone maintenance treatment.

Methods

Presenting frequency, time of appearance and pharmacology treatment of depressive disorder. Depression was verified by psychological testsing. Applied technics were: interview, MMPI, PIE, Mahover test, WAIS, Rorschach test.

Results

The study covered 154 patients on methadone maintenance treatment. 45 (29%) patients had depressive disorder which required pharmacology treatment. Illness was more frequent at female patients comparing with male (35% to 27%). Patients mostly started to use antidepresive drugs approximately three months after they had stopped with heroine use. Sertaline was a drug of first choice used in 30 patients, then Fluoxetine in 7 patients. Improvement of patients’ condition has been indicated by patients’ own reports, higher level of their functionality (social, working functionality) and retest results (lower T score of D scale, MMPI; lower score of emocional dimension Deprivation, PIE).

Conclusion

Significant appearance of depression was noticed in heroine users on methadone maintenance treatment. Illness was usually diagnosed in period of stabilization, after establishing heroin abstinence. So it is recommended to pay attention on patients in period of stabilization and treat with antidepresives if it is necessary.

  • Jeff W, Richard P. M, Wayne H. Methadone maintenance treatment and other opioid replacement therapies, 1997.

  • Domenic A. C, Richard I S, Pharmacotherapy of Depression, 2008.

Type
Abstract
Information
European Psychiatry , Volume 28 , Issue S1: Abstracts of the 21th European Congress of Psychiatry , 2013 , 28-E771
Copyright
Copyright © European Psychiatric Association 2013
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