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COVID-19 pneumonia in an infant with a hemodynamically significant ventricular septal defect

Published online by Cambridge University Press:  12 October 2020

Utkarsh Kohli*
Affiliation:
Section of Pediatric Cardiology, Department of Pediatrics, Comer Children’s Hospital and Pritzker School of Medicine of University of Chicago, Chicago, IL, USA
Julia C. Rosebush
Affiliation:
Section of Infectious Diseases, Department of Pediatrics, Comer Children’s Hospital and Pritzker School of Medicine of University of Chicago, Chicago, IL, USA
Nicola M. Orlov
Affiliation:
Section of Hospital Medicine, Department of Pediatrics, Comer Children’s Hospital and Pritzker School of Medicine of University of Chicago, Chicago, IL, USA
Ahmeneh Ghavam
Affiliation:
Section of Critical Care, Department of Pediatrics, Comer Children’s Hospital and Pritzker School of Medicine of University of Chicago, Chicago, IL, USA
*
Author for correspondence: Utkarsh Kohli, MD, Assistant Professor of Pediatrics, Department of Pediatrics, Section of Cardiology, University of Chicago Medicine, 5841 S, Maryland Ave., Chicago, IL60637, USA. Tel: +1 773 702 6172; Fax: +1 773 702 2319. E-mails: [email protected], [email protected]

Abstract

Reports thus far suggest a mild course for acute COVID-19 infection in children; however, its effects in vulnerable paediatric populations, including children with haemodynamically significant congenital heart disease, have rarely been reported. We therefore report on a 4-month-old Hispanic male with a moderate sized conoventricular ventricular septal defect and pulmonary overcirculation who presented with COVID-19-associated pneumonia.

Type
Brief Report
Copyright
© The Author(s), 2020. Published by Cambridge University Press

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References

Arentz, M, Yim, E, Klaff, L, et al. Characteristics and outcomes of 21 critically ill patients with COVID-19 in Washington state. JAMA 2020; 4720: 20192021.Google Scholar
Belhadjer, Z, Méot, M, Bajolle, F, et al. Acute heart failure in multisystem inflammatory syndrome in children (MIS-C) in the context of global SARS-CoV-2 pandemic. Circulation. 2020; doi: 10.1161/CIRCULATIONAHA.120.048360 CrossRefGoogle Scholar
Cai, W, Buda, S, Schuler, E, Hirve, S, Zhang, W, Haas, W. Risk factors for hospitalized respiratory syncytial virus disease and its severe outcomes. Influenza Other Respir Viruses 2020; doi: 10.1111/irv.12729. doi:10.1111/irv.12729 CrossRefGoogle Scholar
Chen, C, Zhou, Y, Wang, DW. SARS-CoV-2: a potential novel etiology of fulminant myocarditis. Herz 2020; 5: 1012.Google Scholar
Dufort, EM, Koumans, EH, Chow, EJ, et al. Multisystem inflammatory syndrome in children in New York state. N Engl J Med 2020; doi: 10.1056/NEJMoa2021756 CrossRefGoogle Scholar
Eşki, A, Öztürk, GK, Gülen, F, Çiçek, C, Demir, E. Risk factors for influenza virus related severe lower respiratory tract infection in children. Pediatr Infect Dis J 2019; 38: 10901095. doi: 10.1097/INF.0000000000002447 CrossRefGoogle ScholarPubMed
Feldstein, LR, Rose, EB, Horwitz, SM, et al. Multisystem inflammatory syndrome in U.S. children and adolescents. N Engl J Med 2020; doi: 10.1056/NEJMoa2021680 CrossRefGoogle Scholar
Granbom, E, Fernlund, E, Sunnegårdh, J, Lundell, B, Naumburg, E. Respiratory tract infection and risk of hospitalization in children with congenital heart defects during season and off-season: a Swedish National Study. Pediatr Cardiol 2016; 37: 10981105. doi: 10.1007/s00246-016-1397-4 CrossRefGoogle ScholarPubMed
Lu, X, Zhang, L, Du, H, Zhang, J, Li, YY, Qu, J. SARS-CoV-2 infection in children. N Engl J Med 2020; 382: 16631665.CrossRefGoogle ScholarPubMed
Moazenzadeh, M, Jafari, F, Farrokhnia, M, Aliramezany, M. First reported case of unrepaired tetralogy of Fallot complicated with Coronavirus Disease-19 (COVID-19). Cardiol Young. 2020; 11: 14. doi: 10.1017/S1047951120001821 Google Scholar
Shekerdemian, LS, Mahmood, NR, Wolfe, KK, et al. Characteristics and outcomes of children with coronavirus disease 2019 (COVID-19) infection admitted to US and Canadian Pediatric Intensive Care Units. JAMA Pediatr. doi:10.1001/jamapediatrics.2020.1948CrossRefGoogle Scholar
Tan, W, Aboulhosn, J. The cardiovascular burden of coronavirus disease 2019 (COVID-19) with a focus on congenital heart disease. Int J Cardiol 2020; 309: 7077. doi: 10.1016/j.ijcard.2020.03.063 Google ScholarPubMed
Wang, D, Hu, B, Hu, C, et al. Clinical characteristics of 138 hospitalized patients with 2019 novel coronavirus-infected pneumonia in Wuhan, China. JAMA 2020; 323: 10611069.CrossRefGoogle ScholarPubMed
Wu, Z, McGoogan, JM. Characteristics of and important lessons from the coronavirus disease 2019 (COVID-19) outbreak in China: summary of a report of 72 314 cases from the Chinese Center for Disease Control and Prevention. JAMA 2020; 2019: 36.Google Scholar
Xia, W, Shao, J, Guo, Y, Peng, X, Li, Z, Hu, D. Clinical and CT features in pediatric patients with COVID-19 infection: different points from adults. Pediatr Pulmonol. 2020; 55: 11691174. doi: 10.1002/ppul.24718 CrossRefGoogle ScholarPubMed
Yang, X, Yu, Y, Xu, J, et al. Clinical course and outcomes of critically ill patients with SARS-CoV-2 pneumonia in Wuhan, China: a single-centered, retrospective, observational study. Lancet Respir Med 2020; 8: 475481.Google ScholarPubMed
Young, BE, Ong, SWX, Kalimuddin, S, et al. Epidemiologic features and clinical course of patients infected with SARS-CoV-2 in Singapore. JAMA 2020; 323: 14881494.10.1001/jama.2020.3204CrossRefGoogle Scholar
Zheng, F, Liao, C, Fan, QH, et al. Clinical characteristics of children with coronavirus disease 2019 in Hubei, China. Curr Med Sci 2020; 40: 275280. doi: 10.1007/s11596-020-2172-6 CrossRefGoogle ScholarPubMed