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Catastrophic antiphospholipid antibody syndrome associated with ischaemic cardiomyopathy

Published online by Cambridge University Press:  06 January 2025

Jonathan Pacella Open the ORCID record for Jonathan Pacella [Opens in a new window] ,
Jackeline Rodriguez-Smith ,
Haeja Kessler  and
Benjamin S. Mantell
Jonathan Pacella
Affiliation:
The Heart Institute, Cincinnati Children’s Hospital Medical Center, Cincinnati, OH, USA
Jackeline Rodriguez-Smith
Affiliation:
Division of Rheumatology, Cincinnati Children’s Hospital Medical Center, Department of Pediatrics, University of Cincinnati College of Medicine, Cincinnati, OH, USA
Haeja Kessler
Affiliation:
Division of Rheumatology, Cincinnati Children’s Hospital Medical Center, Department of Pediatrics, University of Cincinnati College of Medicine, Cincinnati, OH, USA
Benjamin S. Mantell*
Affiliation:
The Heart Institute, Cincinnati Children’s Hospital Medical Center, Cincinnati, OH, USA Division of Pediatric Cardiology, Department of Pediatrics, University of Cincinnati College of Medicine, Cincinnati, OH, USA
*
Corresponding author: Benjamin Mantell; Email: [email protected]
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Abstract

We report the case of a 16-year-old female with previously diagnosed bilateral sub-segmental pulmonary emboli who presented in cardiogenic shock from depressed biventricular function with cardiac MRI demonstrating concern for microvascular coronary injury. She was ultimately diagnosed with catastrophic antiphospholipid antibody syndrome-induced ischaemic cardiomyopathy, potentially associated with an underlying autoimmune connective tissue disease.

Keywords

catastrophic antiphospholipid antibody syndromeheart failurecardiomyopathy
Type
Brief Report
Information
Cardiology in the Young , First View , pp. 1 - 3
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Copyright
© The Author(s), 2025. Published by Cambridge University Press

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