Hostname: page-component-cd9895bd7-hc48f Total loading time: 0 Render date: 2024-12-22T19:12:57.540Z Has data issue: false hasContentIssue false

A causal relationship between LTP and learning? Has the question been answered by genetic approaches?

Published online by Cambridge University Press:  01 December 1997

Robert Gerlai
Affiliation:
Neuroscience Department, Genentech, Inc. South San Francisco, CA 94080-4990 [email protected]

Abstract

Gene targeting has generated a great deal of data on the molecular mechanisms of long-term potentiation and its potential role in learning and memory. However, the interpretation of some results has been questioned. Compensatory mechanisms and the contribution of genetic background may make it difficult to unequivocally prove the existence of a causal (genetic) link between LTP and learning.

Type
Open Peer Commentary
Copyright
© 1997 Cambridge University Press

Access options

Get access to the full version of this content by using one of the access options below. (Log in options will check for institutional or personal access. Content may require purchase if you do not have access.)