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Are common, harmful, heritable mental disorders common relative to other such non-mental disorders, and does their frequency require a special explanation?

Published online by Cambridge University Press:  09 November 2006

Oliver Mayo*
Affiliation:
CSIRO Livestock Industries, Adelaide, SA5000, Australia
Carolyn Leach*
Affiliation:
School of Molecular and Biomedical Science (Genetics), University of Adelaide, Adelaide, SA5005, Australia

Abstract:

Keller & Miller's (K&M's) conclusion appears to be correct; namely, that common, harmful, heritable mental disorders are largely maintained at present frequencies by mutation-selection balance at many different loci. However, their “paradox” is questionable.

Type
Open Peer Commentary
Copyright
Copyright © Cambridge University Press 2006

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