This article offers an overview of the habitation history of the basin of Ioannina Epirus, from the Early Iron Age to the Roman period. The numerous settlements in this region experienced continuous, often uninterrupted, habitation from the Late Bronze Age to the Hellenistic or even Roman Imperial period. The foundation of fortified settlements/acropoleis in the late fourth to early third century BC should no longer be interpreted as a result of a synoecism, since unfortified villages continued to flourish. From the Augustan period onwards, Romans seem to have settled in the area, although it is also possible that the local population adopted Roman habits.