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Reduction Deformities, Twinning and Mortality in Brazilian Whites and Negroes

Published online by Cambridge University Press:  01 August 2014

N. Freire-Maia  and
J.B.C. Azevedo
N. Freire-Maia*
Affiliation:
Department of Genetics, Federal University of Paraná, Curitiba, Paraná, Brazil
J.B.C. Azevedo
Affiliation:
School of Philosophy, Marilia, SP, Brazil
*
Departamento de Genética (UFPr), Caixa Postal AA, 80000 Curitiba, Paraná, Brasil

Abstract

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A series of house-to-house surveys in Central Brazil revealed 32 cases of reduction deformities of the limbs (brachydactyly, synbrachydactyly, ectrodactyly, amely, adactyly, achiry, apody, etc.) among 58,761 births (0.54 per thousand, being 0.66 per thousand among Whites and 0.43 per thousand among Mulattoes and Negroes). No sibship was found with two or more equally affected singleton members. One case of concordance among twins is referred. There were no parity, inbreeding, race and sex effects. Both hands and both feet were also equally affected. Precocious mortality and twinning were significantly higher among affected individuals. The presence of cleft lip and palate in one of our index patients may also reflect an etiological relationship. Among the sibs, the total incidence of congenital malformations was similar to that generally accepted for general populations.

Type
Research Article
Information
Acta geneticae medicae et gemellologiae: twin research , Volume 26 , Issue 2 , April 1977 , pp. 133 - 140
Copyright
Copyright © The International Society for Twin Studies 1977

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