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The Gm and Inv Factors in Rheumatoid Arthritis

Published online by Cambridge University Press:  01 August 2014

A. Archimandrite*
Affiliation:
Department of Pathologic Physiology, Medical School, State University of Athens, Greece
A. Kalos
Affiliation:
Department of Pathologic Physiology, Medical School, State University of Athens, Greece
G. Papakonstantinou
Affiliation:
Department of Pathologic Physiology, Medical School, State University of Athens, Greece
A. Babionitakis
Affiliation:
Department of Pathologic Physiology, Medical School, State University of Athens, Greece
G. Theodoropoulos
Affiliation:
Department of Pathologic Physiology, Medical School, State University of Athens, Greece
P. Dimitriadis
Affiliation:
Department of Pathologic Physiology, Medical School, State University of Athens, Greece
*
6 Zachou St., Athens (610), Greece

Abstract

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The Gm(1), Gm(2), Gm(4), Gm(12), and Inv(1) factors were studied in the sera of 56 patients suffering from rheumatoid arthritis and 26 from various rheumatic diseases, by the hemagglutination inhibition test, using optimally reacting mixtures of Ragg and Nagg sera. The distribution of these factors was found to agree with that of healthy Greeks. No correlation was found between hypergammaglobulinemia and the discovery of the Gm(1) and Inv(1) factors. The presence of the rheumatoid factor was independent of the Gm and Inv phenotypes.

Type
Short Notes
Copyright
Copyright © The International Society for Twin Studies 1975

References

REFERENCES

Archimandritis, A., Fertakis, A., Stathopoulou, R., Kalos, A., Angelopoulos, B. 1975. Distribution of Gm and Inv factors in two samples of the Greek population. Acta Genet. Med. Gemellol. (Roma), 24: 329331.CrossRefGoogle ScholarPubMed
Deicher, V.H., Schupp, E. 1963. Frequenzen von Gm-Serum-Gruppen bei der primärchronischen Polyarthritis. Z. Rheumaforsch., 22: 6977.Google Scholar
Grubb, R., Laurell, A.B. 1956. Hereditary serologica human serum groups. Acta Pathol. Microbiol. Scand., 39: 390398.Google Scholar
Grubb, R. 1958. Interaction between rheumatoid arthritis sera and human gamma globulin. Acta Haematol., 20: 246252.CrossRefGoogle Scholar
Grubb, R. 1970. The Genetic Markers of Human Immunoglobulins. Berlin/Heidelberg/New York: Springer Verlag.Google Scholar
Harboe, M. 1960. Relation between Gm types and hemagglutinating substances in rheumatoid sera. Acta Pathol. Microbiol. Scand., 50: 89105.CrossRefGoogle ScholarPubMed
Laurell, A.B., Grubb, R. 1958. Complement, complement components, properdin and agglutination promoting factors in rheumatoid arthritis. Acta Pathol. Microbiol. Scand., 43: 310320.CrossRefGoogle ScholarPubMed
Podliachouk, L., Jacqueline, F., Eyquem, A. 1958. Le facteur sérique Gma au cours des rhumatismes inflammatoires chroniques. Ann. Inst. Pasteur, 94: 590597.Google Scholar
Ritter, H., Ropartz, C., Rousseau, P.V., Rivât, L., Walter, H. 1966. Formale Genetik und Populationsgenetik des Inv-Polymorphismus. Blut, 13: 373377.Google Scholar
Strejcek, J., Herzog, P. 1966. Cited by Grubb 1970.Google Scholar
Tiilikainen, A. 1960. Incidence of the Gm serum groups in collagen diseases. Ann. Med. Exp. Fenn., 38: 5155.Google Scholar
Tiilikainen, A. 1965. Gm serum factors in collagen diseases. Proc. 10th Congr. Int. Soc. Blood Transf., Stockholm 1964 [pp. 423426].Google Scholar