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A Case-Control Study of Maternal Gestational Weight Gain and Newborn Birthweight and Birthlength in Twin Pregnancies Complicated by Preeclampsia

Published online by Cambridge University Press:  06 September 2016

B. Luke ,
L. Keith ,
J.A. Lopez-Zeno ,
F.R. Witter  and
E. Saquil
B. Luke
Affiliation:
Division of Maternal-Fetal Medicine, Department of Gynecology and Obstetrics, Johns Hopkins University School of Medicine, Baltimore, Maryland Center for Study of Multiple Births, Chicago Section of Reproductive and Perinatal Epidemiology, Department of Obstetrics and Gynecology, Rush Medical College, Rush-Presbyterian-St. Luke’s Medical Center, Chicago, Illinois
L. Keith*
Affiliation:
Department of Obstetrics and Gynecology, Northwestern University Medical School and Prentice Women’s Hospital of Northwestern Memorial Hospital, Chicago Center for Study of Multiple Births, Chicago Jeanette Kennelly Kroch Center for Twin Studies, Northwestern Memorial Hospital, Chicago
J.A. Lopez-Zeno
Affiliation:
Department of Obstetrics and Gynecology, Northwestern University Medical School and Prentice Women’s Hospital of Northwestern Memorial Hospital, Chicago Department of Obstetrics and Gynecology, The George Washington University School of Medicine, Washington, D.C.
F.R. Witter
Affiliation:
Division of Maternal-Fetal Medicine, Department of Gynecology and Obstetrics, Johns Hopkins University School of Medicine, Baltimore, Maryland
E. Saquil
Affiliation:
Center for Study of Multiple Births, Chicago
*
Northwestern University Medical School, Department of Obstetrics and Gynecology, 333 East Superior Street, Suite 464, Chicago, IL 60611, USA

Abstract

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To evaluate the influence of rate of gestational weight gain on newborn birthweight and birthlength in twin gestations complicated by preeclampsia, 74 cases of preeclampsia in twin pregnancy were matched to 148 non-preeclamptic twin controls for maternal race, height, pregravid weight, age and length of gestation. Total weight gain was significantly higher for all cases versus controls and for mild cases versus controls. However, the rate of early weight gain was lower for severe cases and severe cases with thrombocytopenia compared to their controls. Mean birthweight and birthlength did not differ between cases and controls, although the proportion with birthlength below the 10th percentile was significantly higher among cases than controls. In addition, the proportion of birthweights and birthlengths < 10th percentile was significantly higher among cases than controls. These findings suggest that inadequate early weight gain in twin gestations complicated by preeclampsia results in retarded birthlength and birthweight. The implication of these findings are discussed.

Keywords

Gestational Weight gainPreeclampsiaTwins
Type
Research Article
Information
Acta geneticae medicae et gemellologiae: twin research , Volume 42 , Issue 1 , 1993 , pp. 7 - 15
Copyright
Copyright © The International Society for Twin Studies 1993

References

REFERENCES

1. Abrams, B, Newman, V, Key, T, Parker, J (1989): Maternal weight gain and preterm delivery. Obstet Gynecol 74:577–583.Google Scholar
2. ACOG Technical Bulletin: Management of preeclampsia. No. 91, February (1986).Google Scholar
3. Benirshke, K, Drescoll, S (1974): Pathology of the Human Placenta. New York: Springer-Verlag, pp. 325–327.Google Scholar
4. Bingham, AW (1932): The prevention of obstetric complications by diet and exercise. Am J Obstet Gynecol 23:38–44.Google Scholar
5. Blickstein, I, Shoham-Schwartz, Z, Lancet, M, Borenstein, R (1987): Characterization of the growth-discordant twin. Obstet Gynecol 70:11–14 Google Scholar
6. Brown, JE, Schloesser, PT (1990): Prepregnancy weight status, prenatal weight gain, and the outcome of term twin gestations. Amer J Obstet Gynecol 162:182–186.Google Scholar
7. Hannah, CR (1925): Weight during pregnancy with observations and statistics. Am J Obstet Gynecol 9:854–863.Google Scholar
8. Hediger, ML, Scholl, TO, Belsky, DH, Ances, IG, Salmon, RW (1989): Patterns of weight gain in adolescent pregnancy: Effects on birth weight and preterm delivery. Obstet Gynecol 74:6–12.Google Scholar
9. Long, PA, Oats, JN (1987): Preeclampsia in twin pregnancy. Severity and pathogenesis. Austr N Z J Obstet Gynecol 27:1–5.Google Scholar
10. Luke, B, Witter, FR, Abbey, H, Feng, T, Namnoun, AB, Johnson, TRB (1991): Gestational age-specific birthweights of twins versus singletons. Acta Genet Med Gemellol 40:69–76,Google ScholarPubMed
11. Mabie, BC, Sibai, BM (1987): Hypertensive states of pregnancy. In Pernoll, ML, Benson, RC (eds): Current Obstetric & Gynecol Diagnosi & Treatment, (6th ed) Norwalk, Conn: Appleton & Lange, pp 340–352.Google Scholar
12. McMullan, PF, Marivate, M (1984): Pregnancy-induced hypertension in twin pregnancy. Br J Obstet Gynecol 91:240–243.Google Scholar
13. O’Brien, WF, Knuppel, RA, Scerbo, JC, Rattan, PK (1986): Birth weight in twins: An analysis of discordancy and growth retardation. Obstet Gynecol 67:483–486.Google Scholar
14. Pederson, AL, Worthington-Roberts, B, Hickok, DE (1989): Weight gain patterns during twin gestation. J Am Diet Assoc 89:642–646.CrossRefGoogle ScholarPubMed
15. Scholl, TO, Hediger, ML, Ances, IG, Belsky, DH, Salmon, RW (1990): Weight gain during pregnancy in adolescence: Predictive ability of early weight gain. Obstet Gynecol 75:948–953.Google Scholar
16. Sheehan, HL, Lynch, JB (1973): Pathology of Toxemia of Pregnancy. Baltimore: Williams & Wilkins, pp. 678–679.Google Scholar
17. Stander, HJ, Pastore, JB (1940): Weight changes during pregnancy and puerperium. Am J Obstet Gynecol 39:928–937.Google Scholar
18. Stevens-Simon, C, McAnarney, ER, Coulter, MP (1986): How accurately do pregnant adolescents estimate their weight prior to pregnancy J Adoles Hlth Care 7:250–254.Google Scholar
19. Stewart, AL (1982): The reliability and validity of self-reported weight and height. J Chron Dis 35:259–309.Google Scholar
20. Stouffer, A, Burns, WJ, Burns, KA, Melamed, J, Herman, CE (1988): Early developmental progress of preterm twins discordant for birth weight and risk. Acta Genet Med Gemellol 37:81–87.Google Scholar
21. Tanner, JM (1978): Fetus Into Man. Boston, Massachusetts: Harvard University Press, pp. 40–42.Google Scholar
22. Tompkins, WT, Wiehl, DG, Mitchell, McN R (1955): The underweight patient as an increased obstetric hazard. Am J Obstet Gynecol 69:114–123.CrossRefGoogle ScholarPubMed
23. Young, M (1981): Placental factors and fetal nutrition. Am J Clin Nutr 34:738–43.Google Scholar
24. Villar, J, Belizan, JM (1982): The timing factor in the pathophysiology of the intrauterine growth retardation syndrome. Obstet Gynecol Survey 37:499–506.Google Scholar