Overview
Multidisciplinary research is increasingly focused on identifying potential biological markers of post-traumatic stress disorder (PTSD). Convergent evidence leads to theoretical models of a dysregulation in medial prefrontal inhibitory and limbic arousal networks in PTSD. This symposium provides insight into medial prefrontal and limbic function by examining cognitive, affective and clinical processes in PTSD using event-related potential and functional magnetic resonance imaging methodologies. Working memory and inhibitory processing will be explored in cognitive paradigms, fear processing will be examined in an affective paradigm and neural correlates of treatment response and clinical subtypes of PTSD (dissociation) will showcase clinical applications of this research.