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Introduction

Published online by Cambridge University Press:  04 February 2011

Ilona Roth
Affiliation:
The Open University, Milton Keynes
Payam Rezaie
Affiliation:
The Open University, Milton Keynes
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Summary

The term ‘Autism Spectrum’ currently embraces a cluster of conditions known as Autism Spectrum Disorders or ‘ASD’, that are characterised by impairments in social functioning, verbal and non-verbal communication, together with repetitive and stereotypical patterns of behaviour and interests. Impairments within each of these ‘core’ clinical domains can range in severity from mild to profound, and intellectual disability may be present in more severe cases. The classification of ASD broadly includes classic autism (childhood autism; autistic disorder), Asperger syndrome and Pervasive Developmental Disorder Not Otherwise Specified (PDD-NOS) (Levy et al. 2009). Classic autism is frequently diagnosed around the age of 3 (and may be diagnosed as early as 2 years of age) (Baird et al. 2003; Landa, 2008). Asperger syndrome often presents with more subtle symptoms, and is usually diagnosed later on in childhood (frequently around 11 years of age), and occasionally in adults (Howlin and Asgharian 1999; Toth and King 2008).

While the precise causes of autism remain a mystery, prevalence estimates have risen almost exponentially within the last six decades, making autism a major global concern. Initially considered rare, current estimates suggest that as many as 1% of children under the age of 8 years may have an autism spectrum diagnosis (Baird et al. 2006), with boys being diagnosed up to four times more than girls. More than half a million people are thought to be living with autism in the UK alone (National Autistic Society, 2007), and in the US autism is considerably more common today than it was in the 1980s (Yeargin-Allsopp et al. 2003).

Type
Chapter
Information
Researching the Autism Spectrum
Contemporary Perspectives
, pp. 1 - 16
Publisher: Cambridge University Press
Print publication year: 2011

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References

Abrahams, B.S., Geschwind, D.H. (2008). Advances in autism genetics: on the threshold of a new neurobiology. Nature Reviews Genetics, 9: 341–355.CrossRefGoogle ScholarPubMed
Amaral, D.G., Schumann, C.M., Nordahl, C.W. (2006). Neuroanatomy of autism. Trends in Neurosciences, 31: 137–145.CrossRefGoogle Scholar
,American Psychiatric Association. (2000). Diagnostic and Statistical Manual of Mental Disorders 4th edn. Text Revision (DSMIV TR). Washington DC: American Psychiatric Association.Google Scholar
,American Psychiatric Association. (2010). DSM-5 Development: Disorders usually first diagnosed in infancy, childhood or adolescence. http://www.dsm5.org/ProposedRevisions/Pages/InfancyChildhoodAdolescence.aspx (accessed May 2010).
Amiet, C., Gourfinkel-An, I., Bouzamondo, A., et al. (2008). Epilepsy in autism is associated with intellectual disability and gender: evidence from a meta-analysis. Biological Psychiatry, 64: 577–582.CrossRefGoogle ScholarPubMed
Asperger, H. (1944). Die ‘autistichen psychopathen’ im kindersalter. Archive für Psychiatrie und Nervenkrankenheiten, 117: 76–136. (Reprinted in Autism and Asperger Syndrome, by U. Frith, editor, 1991, Cambridge UK: Cambridge University Press).Google Scholar
Baird, G., Cass, H., Slonims, V. (2003). Diagnosis of autism. British Medical Journal, 327: 488–493.CrossRefGoogle ScholarPubMed
Baird, G., Simonoff, E., Pickles, A., et al. (2006). Prevalence of disorders of the autism spectrum in a population cohort of children in South Thames: the Special Needs and Autism Project (SNAP). Lancet, 368: 210–215.CrossRefGoogle Scholar
Baron-Cohen, S. (1995). Mindblindness: An Essay on Autism and Theory of Mind. London: MIT Press.Google Scholar
Baron-Cohen, S., Leslie, A.M., Frith, U. (1985). Does the autistic child have a ‘theory of mind’? Cognition, 21: 37–46.CrossRefGoogle Scholar
Baron-Cohen, S., Wheelwright, S., Griffin, R., Lawson, J., Hill, J. (2002). The exact mind: empathising and systemising in autism spectrum conditions. In Handbook of Cognitive Development. Oxford: Blackwell.Google Scholar
Bettelheim, B. (1967) The Empty Fortress: Infantile Autism and the Birth of the Self. New York: Free Press.Google Scholar
Bogdashina, O. (2003). Sensory Perceptual Issues in Autism: Different Sensory Experiences – Different Perceptual Worlds. London: Jessica Kingsley.Google Scholar
Casanova, M.F. (2007). The neuropathology of autism. Brain Pathology, 17: 422–433.CrossRefGoogle ScholarPubMed
Courchesne, E., Pierce, K., Schumann, C.M., et al. (2007). Mapping early brain development in autism. Neuron, 56: 399–413.CrossRefGoogle ScholarPubMed
Coury, D. (2010). Medical treatment of autism spectrum disorders. Current Opinion in Neurology, 23: 131–136.CrossRefGoogle ScholarPubMed
Darby, J.K., Clark, L. (1992). Autism syndrome as a final common pathway of behavioural expression for many organic disorders. American Journal of Psychiatry, 149: 146–147. Comment on: American Journal of Psychiatry, 147: 1614–1621.CrossRefGoogle Scholar
DiCicco-Bloom, E., Lord, C., Zwaigenbaum, L., et al. (2006). The developmental neurobiology of autism spectrum disorder. Journal of Neuroscience, 26: 6897–6906.CrossRefGoogle ScholarPubMed
Frith, U. (1991). Autism and Asperger syndrome. Cambridge UK: Cambridge University Press.CrossRefGoogle Scholar
Folstein, S., Rutter, M. (1977). Infantile autism: a genetic study of 21 twin pairs. Journal of Child Psychology and Psychiatry, 18: 297–321.CrossRefGoogle ScholarPubMed
Folstein, S., Rutter, M. (1978). A twin study of individuals with infantile autism. In Autism: A Reappraisal of Concepts and Treatment. New York: Plenum Press, pp. 219–242.CrossRefGoogle Scholar
Frith, U., Morton, J., Leslie, A.M. (1991). The cognitive basis of a biological disorder: Autism. Trends in Neurosciences, 14: 433–438.CrossRefGoogle ScholarPubMed
Geschwind, D.H. (2008). Autism: many genes, common pathways? Cell, 135: 391–395.CrossRefGoogle ScholarPubMed
Geschwind, D.H. (2009). Advances in Autism. Annual Review of Medicine, 60: 367–380.CrossRefGoogle ScholarPubMed
Golan, O., Baron-Cohen, S., Ashwin, E., et al. (2010). Enhancing emotion recognition in children with autism spectrum conditions: an intervention using animated vehicles with real emotional faces. Journal of Autism and Developmental Disorders, 40: 269–279.CrossRefGoogle ScholarPubMed
Gubbay, S.S., Lobascher, M., Kingerlee, P. (1970). A neurological appraisal of autistic children: results of a Western Australian survey. Developmental Medicine and Child Neurology, 12: 422–429.CrossRefGoogle ScholarPubMed
Happé, F. (1999). Autism: Cognitive deficit or cognitive style? Trends in Cognitive Sciences, 3: 216–222.CrossRefGoogle ScholarPubMed
Happé, F., Ronald, A., Plomin, A. (2006). Time to give up on a single explanation for autism. Nature Neuroscience, 9: 1218–1220.CrossRefGoogle ScholarPubMed
Hermelin, B., O'Connor, N. (1964). Effects of sensory input and sensory dominance on severely disturbed, autistic children and on subnormal controls. British Journal of Psychology, 55: 201–206.CrossRefGoogle ScholarPubMed
Hermelin, B., O'Connor, N. (1970). Psychological Experiments with Autistic Children. New York: Pergamon Press.Google Scholar
Hobson, P. (1993). Autism and the Development of Mind. Hove: Lawrence Erlbaum Associates.Google Scholar
Hobson, P. (2002). The Cradle of Thought: Exploring the Origins of Thinking. London: Macmillan.Google Scholar
Honda, H., Shimizu, Y., Rutter, M. (2005). No effect of MMR withdrawal on the incidence of autism: a total population study. Journal of Child Psychology and Psychiatry, 46: 572–579.CrossRefGoogle ScholarPubMed
Howlin, P., Asgharian, A. (1999). The diagnosis of autism and Asperger syndrome: findings from a survey of 770 families. Developmental Medicine and Child Neurology, 41: 834–839.CrossRefGoogle Scholar
Howlin, P., Goode, S., Hutton, J., Rutter, M. (2009). Savant skills in autism: psychometric approaches and parental reports. Philosophical Transactions of the Royal Society of London, Series B: Biological Sciences, 364: 1359–1367.CrossRefGoogle ScholarPubMed
Hughes, J.R., , Melyn, M. (2005). EEG and seizures in autistic children and adolescents: further findings with therapeutic implications. Clinical EEG and Neuroscience, 36: 15–20.CrossRefGoogle ScholarPubMed
Jacob, A. (ed.). (2004). Journal of Autism and Developmental Disorders, Special Issue on Research Methodology – Matching, 34 (1): 1–92.
Kanner, L. (1943). Autistic disturbances of affective contact. Nervous Child, 2: 217–250.Google Scholar
Kolvin, I., Ounsted, C., Roth, M. (1971). Studies in childhood psychoses. V. Cerebral dysfunction and childhood psychoses. British Journal of Psychiatry, 118: 407–414.CrossRefGoogle ScholarPubMed
Lam, K.S.L., Aman, M.G., Arnold, L.E. (2006). Neurochemical correlates of autistic disorder: a review of the literature. Research in Developmental Disabilities, 27: 254–289.CrossRefGoogle ScholarPubMed
Landa, R.J. (2008). Diagnosis of autism spectrum disorders in the first 3 years of life. Nature Clinical Practice: Neurology, 4: 138–147.CrossRefGoogle ScholarPubMed
Levisohn, P.M. (2007). The autism-epilepsy connection. Epilepsia, 48 (S9): 33–35.CrossRefGoogle ScholarPubMed
Levy, S.E., Mandell, D.S., Schultz, R.T. (2009). Autism. Lancet, 374: 1627–1638.CrossRefGoogle ScholarPubMed
Malow, B.A. (2004). Sleep disorders, epilepsy and autism. Mental Retardation and Developmental Disabilities Research Reviews, 10: 122–125.CrossRefGoogle ScholarPubMed
McDougle, C.J., Erickkson, C.A., Stigler, K.A., Posey, D.J. (2005). Neurochemistry in the pathophysiology of autism. Journal of Clinical Psychiatry, 66 (S10): 9–18.Google ScholarPubMed
Minshew, N.J., Keller, T.A. (2010). The nature of brain dysfunction in autism: functional brain imaging studies. Current Opinion in Neurology, 23: 124–130.CrossRefGoogle ScholarPubMed
Minshew, N.J., Williams, D.L. (2007). The new neurobiology of autism: cortex, connectivity and neuronal organisation. Archives of Neurology, 64: 945–950.CrossRefGoogle Scholar
Mottron, L., Dawson, M., Soulières, I., Hubert, B., Burack, J. (2006). Enhanced perceptual functioning in autism: an update, and eight principles of autistic perception. Journal of Autism and Developmental Disorders, 36: 27–43.CrossRefGoogle ScholarPubMed
Murch, S.H., Anthony, A., Casson, D., et al. (2004) Retraction of an interpretation. Lancet, 363: 750. [Retraction statement made by 10 of the 12 original authors who could be contacted referring to the Early Report ‘Ileal-lymphoid-nodular hyperplasia, non-specific colitis, and pervasive developmental disorder in children’ published in The Lancet in 1998]CrossRefGoogle ScholarPubMed
,National Autistic Society (2007). Statistics: How many people have autistic spectrum disorders? http://www.nas.org.uk/nas/jsp/polopoly.jsp?d=235&a=3527 (accessed May 2010).
Palmen, S.J., Engeland, H., Hof, P.R., Schmitz, C. (2004). Neuropathological findings in autism. Brain, 127: 2572–2583.CrossRefGoogle ScholarPubMed
Pardo, C.A., Eberhart, C.G. (2007). The neurobiology of autism. Brain Pathology, 17: 434–447.CrossRefGoogle ScholarPubMed
Pasco, G., Roth, I. (2010). Perspectives on intervention. In Roth, I. with Barson, C., Hoekstra, R., Pasco, G., Whatson, T.The Autism Spectrum in the 21st Century: Exploring Psychology, Biology and Practice. London: Jessica Kingsley.Google Scholar
Richler, J., Huerta, M., Bishop, S.L., Lord, C. (2010). Developmental trajectories of restricted and repetitive behaviours and interests in children with autism spectrum disorders. Development and Psychopathology, 22: 55–69.CrossRefGoogle ScholarPubMed
Rimland, B. (1964). Infantile Autism: The Syndrome and its Implication for a Neural Theory of Behaviour. New York: Prentice Hall.Google Scholar
Rogers, S.J., Ozonoff, S. (2005). Annotation: What do we know about sensory dysfunction in autism? A critical review of the empirical evidence. Journal of Child Psychology and Psychiatry, 46: 1255–1268.CrossRefGoogle ScholarPubMed
Schain, R.J., Yannet, H. (1960). Infantile autism. An analysis of 50 cases and a consideration of certain relevant neurophysiologic concepts. Journal of Pediatrics, 57: 560–567.CrossRefGoogle Scholar
Schumann, C.M., Bloss, C.S., Barnes, C.C., et al. (2010). Longitudinal magnetic resonance imaging study of cortical development through early childhood in autism. Journal of Neuroscience, 30: 4419–4427.CrossRefGoogle ScholarPubMed
Spence, S.J., Schneider, M.T. (2009). The role of epilepsy and epileptiform EEGs in autism spectrum disorders. Pediatric Research, 65: 599–606.CrossRefGoogle ScholarPubMed
Swedo, S. (2008). Report of the DSM-V Neurodevelopmental Disorders Work Group. American Psychiatric Association. http://www.psych.org/MainMenu/Research/DSMIV/DSMV/DSMRevisionActivities/DSMVWorkGroupReports/NeurodevelopmentalDisordersWorkGroupReport.aspx (accessed October 2010).
Swedo, S. (2009). Report of the DSM-V Neurodevelopmental Disorders Work Group. American Psychiatric Association. http://www.psych.org/MainMenu/Research/DSMIV/DSMV/DSMRevisionActivities/DSM-V-Work-Group-Reports/Neurodevelopmental-Disorders-Work-Group-Report.aspx (accessed October 2010).
Thomas, M.S., Annaz, D., Ansari, D., et al. (2009). Using developmental trajectories to understand developmental disorders. Journal of Speech, Language and Hearing Research, 52: 336–358.CrossRefGoogle ScholarPubMed
Toth, K., King, B.H. (2008). Asperger's syndrome: diagnosis and treatment. American Journal of Psychiatry, 165: 958–963.CrossRefGoogle ScholarPubMed
Verhoeven, J.S., DeCock, P., Lagae, L., Sunaert, S. (2010). Neuroimaging of autism. Neuroradiology, 52: 3–14.CrossRefGoogle ScholarPubMed
Wakefield, A.J., Murch, S.H., Anthony, A., et al. (1998). RETRACTED: Ileal-lymphoid-nodular hyperplasia, non-specific colitis, and pervasive developmental disorder in children. Lancet, 351: 637–641.CrossRefGoogle ScholarPubMed
Weiss, L.A. (2009). Autism genetics: emerging data from genome-wide copy number and single nucleotide polymorphism scans. Expert Review of Molecular Diagnostics, 9: 795–803.CrossRefGoogle ScholarPubMed
Wing, L. (1981). Asperger's syndrome: a clinical account. Psychological Medicine, 11: 115–129.CrossRefGoogle ScholarPubMed
,World Health Organization (1993). The ICD-10 Classification of Mental and Behavioural Disorders: Diagnostic Criteria for Research. Geneva: World Health Organization.Google Scholar
Yeargin-Allsopp, M., Rice, C., Karapurkar, T., et al. (2003). Prevalence of autism in a US metropolitan area. Journal of the American Medical Association, 289: 49–55.Google Scholar

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