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Chapter 33 - Lipid Management

from Section III - Care of the Elderly by Organ System

Published online by Cambridge University Press:  30 June 2022

By
Phil Mendys ,
Adam Moskowitz  and
Ross J. Simpson
Edited by
Jan Busby-Whitehead ,
Samuel C. Durso ,
Christine Arenson ,
Rebecca Elon ,
Mary H. Palmer  and
William Reichel
Jan Busby-Whitehead
Affiliation:
University of North Carolina, Chapel Hill
Samuel C. Durso
Affiliation:
The Johns Hopkins University, Maryland
Christine Arenson
Affiliation:
Thomas Jefferson University, Philadelphia
Rebecca Elon
Affiliation:
The Johns Hopkins University School of Medicine
Mary H. Palmer
Affiliation:
University of North Carolina, Chapel Hill
William Reichel
Affiliation:
Georgetown University Medical Center
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Summary

Our understanding of the causal role of serum lipids in atherosclerosis and the development of myocardial infarction and stoke in the elderly is evolving rapidly. We know now that aggressive lipid management can help stabilize atherosclerosis and reduce new and recurrent infarctions in most adults under age 75 and evidence-based guidelines support lipid management with diet, exercise, and medications for older adults under age 75, with the safety and efficacy of statins and now the PCSK-9s well established. For older adults, particularly those under age 85, similar trends persist, but the data is less well established and individualization of therapy with dose adjustment, based on expected quality of life and expected benefit and risks, is encouraged. The availability of newly developed drugs and clinical trials in the elderly to control serum lipids is expected to provide additionally guidance for treatment in older patients in the near future.

Keywords

lipidscardiovascular diseasestatinselderlyrisk–benefitadherence
Type
Chapter
Information
Reichel's Care of the Elderly
Clinical Aspects of Aging
 , pp. 407 - 417
Publisher: Cambridge University Press
Print publication year: 2022

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References

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