Book contents
- Frontmatter
- Contents
- Contributors
- Preface
- 1 The epidemiology of preterm labour and delivery
- 2 Biology of preterm labour
- 3 Transcriptional regulation of labour-associated genes
- 4 Fetal outcome following preterm delivery
- 5 The prediction of preterm labour
- 6 Prevention of preterm labour
- 7 Management of preterm premature ruptured membranes
- 8 Management of threatened preterm labour
- 9 Management of preterm labour with specific complications
- 10 Anaesthetic issues in preterm labour, and intensive care management of the sick parturient
- 11 Management of the preterm neonate
- 12 Organisation of high risk obstetric and neonatal services
- 13 The management of pregnancy and labour
- 14 Treating the preterm infant – the legal context
- Index
- References
4 - Fetal outcome following preterm delivery
Published online by Cambridge University Press: 07 August 2009
- Frontmatter
- Contents
- Contributors
- Preface
- 1 The epidemiology of preterm labour and delivery
- 2 Biology of preterm labour
- 3 Transcriptional regulation of labour-associated genes
- 4 Fetal outcome following preterm delivery
- 5 The prediction of preterm labour
- 6 Prevention of preterm labour
- 7 Management of preterm premature ruptured membranes
- 8 Management of threatened preterm labour
- 9 Management of preterm labour with specific complications
- 10 Anaesthetic issues in preterm labour, and intensive care management of the sick parturient
- 11 Management of the preterm neonate
- 12 Organisation of high risk obstetric and neonatal services
- 13 The management of pregnancy and labour
- 14 Treating the preterm infant – the legal context
- Index
- References
Summary
Introduction
Severe prematurity is the commonest cause of death and disability in perinatal medicine. It is essential to provide parents whose baby is at risk of being delivered extremely prematurely with an accurate and honest assessment of their baby's chance of survival and, if the child does survive to go home, inform them of the risk of severe disability in later life. With increasing survival of very immature babies the focus has shifted, to an extent, to discussions with the parents of whether the child is likely to be disabled and the severity of any subsequent disability. Predictions of severe disability, including cerebral palsy, severe learning problems, blindness and deafness, are reasonably accurate on a statistical basis, but in recent years it has become increasingly apparent that babies who survive into childhood with no severe neurological disability may show significant problems at school age, and these may, in turn, cause considerable distress to the family. This chapter reviews the best evidence on risk of death and disability in severely prematurely born babies.
The chapter is divided into five sections including a general critique of preterm delivery outcome studies, as well as reviews of mortality, severe disability, less severe short-term morbidity and long-term outcome into adolescence.
Methodology of outcome reviews
The medical literature on survival and disability rates varies considerably and this variation is dependent on a number of methodological factors.
- Type
- Chapter
- Information
- Preterm LabourManaging Risk in Clinical Practice, pp. 109 - 132Publisher: Cambridge University PressPrint publication year: 2005