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Case 32 - Metastatic Renal Cell Carcinoma of the Parotid Gland

Published online by Cambridge University Press:  19 November 2019

By
Alessandro Franchi ,
Luca Novelli ,
Cecilia Taverna ,
Michele Pietragalla  and
Giuseppe Spinelli
Edited by
Alessandro Franchi
Alessandro Franchi
Affiliation:
Università degli Studi di Firenze, Italy
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Summary

A 59-year-old female with a 9-year history of clear cell renal cell carcinoma (RCC) with metastases to lungs, pancreas, and gallbladder, treated by nephrectomy, adjuvant chemotherapy, and biological therapy, presented with a 4-month history of swelling of the parotid region, associated with pain and loss of function of the frontal branch of the facial nerve. Clinical examination confirmed the presence of a firm subcutaneous lesion, with focal ulceration of the overlying skin.

Type
Chapter
Information
Pearls and Pitfalls in Head and Neck Pathology , pp. 69 - 71
Publisher: Cambridge University Press
Print publication year: 2019

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References

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Majewska, H, Skálová, A, Radecka, K, Stodulski, D, Hyrcza, M, Stankiewicz, C, et al. Renal clear cell carcinoma metastasis to salivary glands – a series of 9 cases: clinico-pathological study. Polish J Pathol. 2016;67:39–45.CrossRefGoogle ScholarPubMed
Som, PM, Norton, KI, Shugar, JM, Reede, DL, Norton, L, Biller, HF, et al. Metastatic hypernephroma to the head and neck. AJNR Am J Neuroradiol. 1987;8:1103–1106.Google Scholar
Said-Al-Naief, N, Klein, MJ. Clear cell entities of the head and neck: a selective review of clear cell tumors of the salivary glands. Head Neck Pathol. 2008;2:111–115.CrossRefGoogle ScholarPubMed
McHugh, JB, Hoschar, AP, Dvorakova, M, et al. p63 immunohistochemistry differentiates salivary gland oncocytoma and oncocytic carcinoma from metastatic renal cell carcinoma. Head Neck Pathol 2007;1:123–131.CrossRefGoogle ScholarPubMed

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