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Chapter 70 - Breast Cancer in Pregnancy

from Section 12 - Malignant Conditions in Pregnancy

Published online by Cambridge University Press:  23 February 2023

By
Nathaniel Bouganim  and
Amira El-Messidi
Edited by
Amira El-Messidi  and
Alan D. Cameron
Amira El-Messidi
Affiliation:
McGill University, Montréal
Alan D. Cameron
Affiliation:
University of Glasgow
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Summary

A 32-year-old primigravida at 16+1 weeks’ gestation is referred by her primary care provider to your high-risk obstetrics unit at a tertiary center for evaluation of a breast lump. Routine prenatal investigations, fetal sonography, and aneuploidy screening were normal. The patient does not have any obstetric complaints and takes only prenatal vitamins.

Keywords

Breast cancer, pregnancy, gestational breast cancerClinical presentationInvestigations, core needle biopsy mammography, bone scan, sentinel node biopsyChemotherapy, surgery, radiotherapyPerinatal risks, complications, maternal-fetal morbidity, adverse outcomeAntepartum, intrapartum, postpartum managementTrastuzumab, tamoxifen, fetal teratogenicityObstetric deliveryContraception
Type
Chapter
Information
OSCEs in Obstetrics and Maternal-Fetal Medicine
An Evidence-Based Approach
 , pp. 889 - 897
Publisher: Cambridge University Press
Print publication year: 2023

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References

Suggested Readings

Amant, F, Deckers, S, Van Calsteren, K, et al. Breast cancer in pregnancy: recommendations of an international consensus meeting. Eur J Cancer. 2010;46(18):3158–3168.Google Scholar
Amant, F, Han, SN, Gziri, MM, et al. Management of cancer in pregnancy. Best Pract Res Clin Obstet Gynaecol. 2015;29(5):741–753.CrossRefGoogle ScholarPubMed
Azim, HA Jr, Santoro, L, Pavlidis, N, et al. Safety of pregnancy following breast cancer diagnosis: a meta-analysis of 14 studies. Eur J Cancer. 2011;47(1):74–83.Google Scholar
Case, AS. Pregnancy-associated breast cancer. Clin Obstet Gynecol. 2016;59(4):779–788.Google Scholar
Macdonald, HR. Pregnancy associated breast cancer. Breast J. 2020;26(1):81–85.Google Scholar
Martínez, MT, Bermejo, B, Hernando, C, et al. Breast cancer in pregnant patients: A review of the literature. Eur J Obstet Gynecol Reprod Biol. 2018; 230:222–227.CrossRefGoogle ScholarPubMed
Paris, I, Di Giorgio, D, Carbognin, L, et al. Pregnancy-associated breast cancer: a multidisciplinary approach. Clin Breast Cancer. 2020;S1526–8209(20):30173–30177.Google Scholar
Royal College of Obstetricians and Gynaecologists (RCOG). Pregnancy and breast cancer. Green-Top Guideline No. 12. London: RCOG; 2011.Google Scholar
Shachar, SS, Gallagher, K, McGuire, K, et al. Multidisciplinary management of breast cancer during pregnancy. Oncologist. 2017;22(3):324–334. [Correction in Oncologist. 2018 Jun;23(6):746]Google Scholar

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