Book contents
- Modern Management of Uterine Fibroids
- Modern Management of Uterine Fibroids
- Copyright page
- Contents
- Contributors
- Foreword
- Chapter 1 Pathophysiology of Uterine Fibroids
- Chapter 2 Evaluation of Uterine Fibroids Using Two-Dimensional and Three-Dimensional Ultrasonography
- Chapter 3 Ulipristal and Other Medical Interventions for Treatment of Uterine Fibroids
- Chapter 4 The Role of Magnetic Resonance Imaging in the Management of Fibroids
- Chapter 5 Fibroids and Fertility
- Chapter 6 Fibroids and Reproduction
- Chapter 7 Open Myomectomy
- Chapter 8 Laparoscopic and Robotic Myomectomy
- Chapter 9 Principles and Technique of Laparoscopic Myomectomy
- Chapter 10 Uterine Fibroids
- Chapter 11 Total Laparoscopic Hysterectomy for the Fibroid Uterus
- Chapter 12 Hysteroscopic Resection of Submucosal Fibroids
- Chapter 13 Modern Management of Intramural Myomas
- Chapter 14 Outpatient Myomectomy
- Chapter 15 Vaginal Hysterectomy with Fibroids
- Chapter 16 Leiomyosarcoma
- Chapter 17 MRI-Guided Ultrasound Lysis of Fibroids
- Chapter 18 Embolization for the Management of Uterine Fibroids
- Chapter 19 Uterine Fibroids in Postmenopausal Women
- Appendix: Video Captions
- Index
- References
Chapter 19 - Uterine Fibroids in Postmenopausal Women
Published online by Cambridge University Press: 10 October 2020
- Modern Management of Uterine Fibroids
- Modern Management of Uterine Fibroids
- Copyright page
- Contents
- Contributors
- Foreword
- Chapter 1 Pathophysiology of Uterine Fibroids
- Chapter 2 Evaluation of Uterine Fibroids Using Two-Dimensional and Three-Dimensional Ultrasonography
- Chapter 3 Ulipristal and Other Medical Interventions for Treatment of Uterine Fibroids
- Chapter 4 The Role of Magnetic Resonance Imaging in the Management of Fibroids
- Chapter 5 Fibroids and Fertility
- Chapter 6 Fibroids and Reproduction
- Chapter 7 Open Myomectomy
- Chapter 8 Laparoscopic and Robotic Myomectomy
- Chapter 9 Principles and Technique of Laparoscopic Myomectomy
- Chapter 10 Uterine Fibroids
- Chapter 11 Total Laparoscopic Hysterectomy for the Fibroid Uterus
- Chapter 12 Hysteroscopic Resection of Submucosal Fibroids
- Chapter 13 Modern Management of Intramural Myomas
- Chapter 14 Outpatient Myomectomy
- Chapter 15 Vaginal Hysterectomy with Fibroids
- Chapter 16 Leiomyosarcoma
- Chapter 17 MRI-Guided Ultrasound Lysis of Fibroids
- Chapter 18 Embolization for the Management of Uterine Fibroids
- Chapter 19 Uterine Fibroids in Postmenopausal Women
- Appendix: Video Captions
- Index
- References
Summary
Uterine fibroids (UFs), also known as leiomyomas or myomas, are the most common benign gynaecologic neoplasm in premenopausal women worldwide and estimated to occur in 7–8 women out of 10 during their lifetime [1]. The aetiology behind UFs is thought to involve genetic, biologic, and environmental factors [1]. Growth factors have been implicated in certain molecular processes involved in the pathogenesis of UFs which includes inflammation, cell proliferation, fibrosis, and angiogenesis [2]. Numerous studies and clinical observations have shown that growth of UFs is dependent on ovarian steroid hormones. Accordingly, there have been no documented cases of UFs prior to menarche, while its prevalence increases with age and peaks during the fifth decade of life [3]. Consequently, the risk tends to decline after menopause, especially in women over the age of 70 years [4]. About 20% of UF patients present with heavy or abnormal bleeding and pelvic pressure; additionally, UFs can cause infertility or loss of pregnancy [2].
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- Modern Management of Uterine Fibroids , pp. 184 - 189Publisher: Cambridge University PressPrint publication year: 2020