Book contents
- Handbook of Industrial Crystallization
- Handbook of Industrial Crystallization
- Copyright page
- Contents
- Contributors
- Preface to the First Edition
- Preface to the Second Edition
- Preface to the Third Edition
- Chapter 1 Solutions and Solution Properties
- Chapter 2 Crystals and Crystal Growth
- Chapter 3 Crystal Nucleation
- Chapter 4 The Influence of Impurities and Additives on Crystallization
- Chapter 5 Molecular Modeling Applications in Crystallization
- Chapter 6 Crystallization Process Analysis by Population Balance Modeling
- Chapter 7 Selection and Design of Industrial Crystallizers
- Chapter 8 Precipitation Processes
- Chapter 9 Melt Crystallization
- Chapter 10 Crystallizer Mixing
- Chapter 11 Monitoring and Advanced Control of Crystallization Processes
- Chapter 12 Batch Crystallization
- Chapter 13 Crystallization in the Pharmaceutical Industry
- Chapter 14 Crystallization of Proteins
- Chapter 15 Crystallization in Foods
- Chapter 16 Precipitation and Crystallization of Pigments
- Index
- References
Chapter 11 - Monitoring and Advanced Control of Crystallization Processes
Published online by Cambridge University Press: 14 June 2019
- Handbook of Industrial Crystallization
- Handbook of Industrial Crystallization
- Copyright page
- Contents
- Contributors
- Preface to the First Edition
- Preface to the Second Edition
- Preface to the Third Edition
- Chapter 1 Solutions and Solution Properties
- Chapter 2 Crystals and Crystal Growth
- Chapter 3 Crystal Nucleation
- Chapter 4 The Influence of Impurities and Additives on Crystallization
- Chapter 5 Molecular Modeling Applications in Crystallization
- Chapter 6 Crystallization Process Analysis by Population Balance Modeling
- Chapter 7 Selection and Design of Industrial Crystallizers
- Chapter 8 Precipitation Processes
- Chapter 9 Melt Crystallization
- Chapter 10 Crystallizer Mixing
- Chapter 11 Monitoring and Advanced Control of Crystallization Processes
- Chapter 12 Batch Crystallization
- Chapter 13 Crystallization in the Pharmaceutical Industry
- Chapter 14 Crystallization of Proteins
- Chapter 15 Crystallization in Foods
- Chapter 16 Precipitation and Crystallization of Pigments
- Index
- References
Summary
Crystallization is one of the main separation and purification processes in the pharmaceutical, biotechnology, food, microelectronics, fine and bulk chemicals industries. The production of more than 70 percent of all solid products involves at least one crystallization as a key processing step, which can have a significant effect on the overall performance of the entire production process and the properties of the final product. The control of crystallization processes is challenging because of the highly nonlinear dynamics, large variations in length and time scales at which the various simultaneous mechanisms occur, variations in crystallization rates over time owing to variations in the impurity profiles of chemical feedstocks, unexpected polymorphic transformations, and nonideal mixing conditions.
- Type
- Chapter
- Information
- Handbook of Industrial Crystallization , pp. 313 - 345Publisher: Cambridge University PressPrint publication year: 2019
References
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