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9 - Breast Cancer in African Populations

Published online by Cambridge University Press:  02 December 2019

By
Konduru S. Sastry  and
Lotfi Chouchane
Edited by
Muntaser E. Ibrahim  and
Charles N. Rotimi
Muntaser E. Ibrahim
Affiliation:
University of Khartoum
Charles N. Rotimi
Affiliation:
National Human Genome Research Institute/NIH
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Summary

Breast cancer is the second most common form of malignant neoplasia in the world, with an estimated 1.67 million new cancer cases diagnosed in 2012, accounting for 25 percent of all cancers (Ferlay et al. 2013). It is the most frequently diagnosed type of cancer in women in both the developed and less developed regions. The biological and pathological diversity of this disease as influenced by distinct phenotypes, differences in prognosis, and mixed responses to treatment limit the progress to reduce the burden of this disease (Kestler et al. 2011). Thus, the incidence of breast cancer is rising in many parts of the world, especially in developing countries. Breast cancer does not manifest equally in various regions of the world. Its incidence is higher in North America and Northern and Western Europe compared to Southern Europe, and lowest in Africa and Asia (Ferlay et al. 2013).

Type
Chapter
Information
The Genetics of African Populations in Health and Disease , pp. 199 - 216
Publisher: Cambridge University Press
Print publication year: 2019

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