The Horthemels and Hémery sisters were two sets of sister-printmakers living and working in eighteenth-century Paris. Despite their relative obscurity within contemporary scholarship, these women were, according to their Parisian contemporaries, some of the most well-respected graveuses en taille-douce: female intaglio engravers who produced printed images for circulation within the art market. By providing an in-depth exploration of the sisters’ careers – including their preliminary artistic training, roles within the family workshop, and personal and professional collaborations beyond the familial atelier – this chapter provides a more nuanced understanding of the eighteenth-century Parisian print workshop and prominent printmaking families, many of whom would have struggled without the support and labour of mothers, wives, and daughters. While the sisters’ familial and professional networks provided access to opportunities and certainly aided their success, both the Horthemels and Hémery sisters exercised independent ambition and initiative to ensure their reputations and future careers.