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117 - Palmitoylethanolamide (PEA)

from Part 1 - Nutraceuticals and Medical Food Preparations for Chronic Pain

Published online by Cambridge University Press:  05 October 2012

Howard S. Smith  and
Marco Pappagallo
Edited in consultation with
Stephen M. Stahl
Howard S. Smith
Affiliation:
Academic Director of Pain Management, Albany Medical College
Marco Pappagallo
Affiliation:
Director, Pain Management and Medical Mentoring, New York Medical Home for Chronic Pain
Stephen M. Stahl
Affiliation:
University of California, San Diego
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Information
Essential Pain Pharmacology
The Prescriber's Guide
 , pp. 530 - 532
Publisher: Cambridge University Press
Print publication year: 2012

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References

Aloe, LLeon, ALevi-Montalcini, RA proposed autacoids mechanism controlling mastocyte behaviourAgents Acts 1993 39 C145Google Scholar
Calignano, ALa Rana, GPiomelli, DAntinociceptive activity of the endogenous fatty acid amide, palmitylethanolamideEur J Pharmacol 2001 419 191Google Scholar
Darmani, NAIzzo, AADegenhardt, BInvolvement of the cannabimimetic compound, N-palmitoylethanolamine, in inflammatory and neuropathic conditions: review of the available pre-clinical data, and first human studiesNeuropharmachology 2005 48 1154Google Scholar
http://www.iocob.nl/english-articles/palmitoylethanolamide-normast-for-neuropathic-pain-3.html 2011
Indraccolo, UBarbieri, FEffect of palmitoylethanolamide–polydatin combination on chronic pelvic pain associated with endometriosis: preliminary observations. J Obstetr Gynecol Reprod Biol 2010 150 76Google Scholar
Jaggar, SIHasnie, FSSellaturay, SRice, ACThe anti-hyperalgesic actions of the cannabinoid anandamide and the putative CB2 receptor agonist palmitoylethanolamide in visceral and somatic inflammatory painPain 1998 76 189Google Scholar
Petrosino, SPalazzo, Ede Novellis, VChanges in spinal and supraspinal endocannabinoid levels in neuropathic ratsNeuropharmacology 2007 52 415Google Scholar

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