Based upon their widespread effective use and reported results from meta-analysis of five RCTs, topical NSAIDs are the analgesic treatment of choice for traumatic corneal abrasions (CAs). There are no studies on the use of oral or parenteral NSAIDs in CA. Opioids have not been directly assessed as analgesics for CA. Oxycodone with acetaminophen (paracetamol) is useful as a rescue analgesic in patients failing topical NSAIDs. The ophthalmology literature makes frequent reference to the analgesic utility of bandage contact lenses in CA. However, this approach is not recommended for ED use since NSAIDs work well and the contact lens approach is associated with potential infectious complications, and limited study of cycloplegic use in CA is available. There has been limited study of cycloplegic use in CA. An RCT showed no benefit as assessed by either pain score improvement or need for rescue oral analgesics.