A series of greenhouse studies examined the effectiveness of PRE- and POST-applied sulfentrazone in controlling purple and yellow nutsedge as influenced by selective tissue exposure. In addition, 14C-sulfentrazone was utilized to contrast absorption and translocation resulting from these exposures. Consistent control with preemergence applications to germinating tubers was obtained with a combined root and shoot zone exposure. Yellow nutsedge was more susceptible than purple nutsedge. Performance of the separate root and shoot zone exposure was soil pH- and nutsedge-species dependent. POST-foliar applications to established nutsedge were more effective when sulfentrazone was allowed to contact the soil surface. 14C-sulfentrazone was readily absorbed by the roots and translocated to the foliage of both species in hydroponic culture.