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Chapter 9 - Considerations for Operations Involving Deep Hypothermic Circulatory Arrest
- By Pingping Song, Joseph E Arrowsmith
Edited by Florian Falter, Albert C. Perrino, Jr, Robert A. Baker
Book:

Cardiopulmonary Bypass

Published online:

24 October 2022

Print publication:

10 November 2022, pp 80-91
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Summary

Deep hypothermic circulatory arrest (DHCA), either alone or in combination with other perfusion strategies, has become the mainstay of vital organ protection for a variety of pathologies and surgical procedures that necessitate the complete cessation of blood flow. DHCA provides a near blood-less operating field, albeit of limited duration, while ameliorating the major adverse consequences of vital organ ischemia.Cooling of the brain – the organ at greatest ischemic risk – reduces cerebral metabolic rate, extending the period of "safe" ischemia from 3-4 minutes at normothermia to >20 minutes.