Skip to main content Accessibility help

We use cookies to distinguish you from other users and to provide you with a better experience on our websites. Close this message to accept cookies or find out how to manage your cookie settings.

Close cookie message
×
  1. Home
  2. Search

Refine search

Refine search

Access:
Content type:
Publication date:
Apply   From and To filters
Subject: Show more
Journals Show more
Publishers: Show more
Societies Show more
Series: Show more
Collections: Show more

Actions for selected content:

Select all | Deselect all
  • View selected items
  • Export citations
  • Download PDF (zip)
  • Save to Kindle
  • Save to Dropbox
  • Save to Google Drive

Save Search

You can save your searches here and later view and run them again in "My saved searches".

Please provide a title, maximum of 40 characters.
Cancel
×

12 results

  • Preface

  • Edited by Charles N. Serhan, Peter A. Ward, University of Michigan, Ann Arbor, Derek W. Gilroy, University College London
  • With contributions by Samir S. Ayoub
  • Book:
    Fundamentals of Inflammation
    Published online:
    05 April 2014
    Print publication:
    26 April 2010, pp xiii-xiv

  • Summary

    The acute inflammatory response is the body's first system of alarm signals that are directed toward containment and elimination of microbial invaders. Uncontrolled inflammation has emerged as a pathophysiologic basis to many of the widely occurring diseases in the general population that were not initially known to be linked to events in the inflammatory response. These include cardiovascular diseases and neurodegenerative diseases (including Alzheimer's disease), and it has now become apparent that inflammation is an important component of cancer progression and the persistence of neuropathic pain. These are diseases that cross many disciplines. To better manage treatment, diagnosis, and prevention of diseases, multidisciplinary research efforts are under way in both academic and industry settings. Since knowledge of the acute inflammatory response in itself spans many disciplines, the editors' mission is to provide in this text an introduction to the cell types, chemical mediators, and general mechanisms that are involved in this primordial first response of the host to invasion. It is also now clear that the termination or the resolution of the acute inflammatory response is an active process, which is pivotal and is the outcome of the acute response. As an endogenous programmed response, the terrain of resolution holds many new possibilities for treatment and prevention of uncontrolled inflammation in a wide range of diseases.

Fundamentals of Inflammation
  • Edited by Charles N. Serhan, Peter A. Ward, Derek W. Gilroy
  • With contributions by Samir S. Ayoub
  • Published online:
    05 April 2014
    Print publication:
    26 April 2010
  • The acute inflammatory response is the body's first system of alarm signals that are directed toward containment and elimination of microbial invaders. Uncontrolled inflammation has emerged as a pathophysiologic basis for many widely occurring diseases in the general population that were not initially known to be linked to the inflammatory response, including cardiovascular disease, asthma, arthritis, and cancer. To better manage treatment, diagnosis, and prevention of these wide-ranging diseases, multidisciplinary research efforts are underway in both academic and industry settings. This book provides an introduction to the cell types, chemical mediators, and general mechanisms of the host's first response to invasion. World-class experts from institutions around the world have written chapters for this introductory text. The text is presented as an introductory springboard for graduate students, medical scientists, and researchers from other disciplines wishing to gain an appreciation and working knowledge of current cellular and molecular mechanisms fundamental to inflammation.