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Recent studies postulated the viability of a suite of metabolic pathways in Enceladus’ ocean motivated by the detection of H2 and CO2 in the plumes – evidence for available free energy for methanogenesis driven by hydrothermal activity at the moon's seafloor. However, these have not yet been explored in detail. Here, a range of experiments were performed to investigate whether microbial iron reduction could be a viable metabolic pathway in the ocean by iron-reducing bacteria such as Geobacter sulfurreducens. This study has three main outcomes: (i) the successful reduction of a number of crystalline Fe(III)-bearing minerals predicted to be present at Enceladus was shown to take place to differing extents using acetate as an electron donor; (ii) substantial bacterial growth in a simulated Enceladus ocean medium was demonstrated using acetate and H2(g) separately as electron donors; (iii) microbial iron reduction of ferrihydrite was shown to partially occur at pH 9, the currently accepted value for Enceladus’ ocean, whilst being severely hindered at the ambient ocean temperature of 0°. This study proposes the possibilities for biogeochemical iron cycling in Enceladus’ ocean, suggesting that a strain of iron-reducing bacteria can effectively function under Enceladus-like conditions.
The collective response of electrons in an ultrathin foil target irradiated by an ultraintense (${\sim}6\times 10^{20}~\text{W}~\text{cm}^{-2}$) laser pulse is investigated experimentally and via 3D particle-in-cell simulations. It is shown that if the target is sufficiently thin that the laser induces significant radiation pressure, but not thin enough to become relativistically transparent to the laser light, the resulting relativistic electron beam is elliptical, with the major axis of the ellipse directed along the laser polarization axis. When the target thickness is decreased such that it becomes relativistically transparent early in the interaction with the laser pulse, diffraction of the transmitted laser light occurs through a so called ‘relativistic plasma aperture’, inducing structure in the spatial-intensity profile of the beam of energetic electrons. It is shown that the electron beam profile can be modified by variation of the target thickness and degree of ellipticity in the laser polarization.
The enterprise budget, whole farm cash flow, and income statement are fundamental tools of farm and ranch management. The “Microcomputer Budget Management System” (MBMS) is a microcomputer software package that facilitates the storage and use of information for crop and livestock budgeting. It performs the calculations for several1 enterprise budgeting formats and for preparation of whole farm resource use reports and financial statements. The MBMS also includes internal machinery and irrigation cost calculation routines.
MBMS was developed for use by extension staff, researchers, lenders, consultants, and operators of diversified farms and ranches with many enterprises that use enterprise and whole farm budgeting for analysis and planning activities. The flexibility and detailed nature of the program requires the user to have knowledge of enterprise budgeting and operation of complex computer programs. This paper presents a discussion of the features and capabilities of the software and the computational procedures used in the cost calculations.
Despite improvements in outcomes after completion of the Fontan circulation, long-term functional state varies. We sought to identify pre- and postoperative characteristics associated with overall function.
Methods and Results
We analyzed data from 476 survivors with the Fontan circulation enrolled in the Pediatric Heart Network Fontan Cross-sectional Study. Mean age at creation of the Fontan circulation was 3.4 plus or minus 2.1 years, with a range from 0.7 to 17.5 years, and time since completion was 8.7 plus or minus 3.4 years, the range being from 1.1 to 17.3 years. We calculated a functional score for the survivors by averaging the percentile ranks of ventricular ejection fraction, maximal consumption of oxygen, the physical summary score for the Child Health Questionnaire, and a function of brain natriuretic peptide. The mean calculated score was 49.5 plus or minus 17.3, with a range from 3 to 87. After adjustment for time since completion of the circulation, we found that a lower score, and hence worse functional state, was associated with: right ventricular morphology (p less than 0.001), higher ventricular end-diastolic pressure (p equals 0.003) and lower saturations of oxygen (p equals 0.047) prior to completion of the Fontan circulation, lower income for the caregiver (p equals 0.003), and, in subjects without a prior superior cavopulmonary anastomosis, arrhythmias after completion of the circulation (p equals 0.003). The model explained almost one-fifth (18%) of the variation in the calculated scores. The score was not associated with surgical centre, sex, age, weight, fenestration, or the period of stay in hospital after completion of the Fontan circuit. A validation model, using 71 subjects randomly excluded from initial analysis, weakly correlated (R equals 0.17, p equals 0.16) with the score calculated from the dataset.
Conclusions
Right ventricular morphology, higher ventricular end-diastolic pressure and lower saturations of oxygen prior to completion of the Fontan circuit, lower income for the provider of care, and arrhythmias after creation of the circuit, are all associated with a worse functional state. Unmeasured factors also influence outcomes.
More than 15 years—nine election cycles—have passed since a comprehensive set of state legislative election data was compiled and made available to researchers and practitioners: the Inter-University Consortium for Political and Social Research's (ICPSR) State Legislative Election Returns in the United States dataset (Study #8907) collected by Malcolm Jewell (Jewell 1991) and containing observations from 1967 to 1988. With this hiatus in mind, we set out at various times initially—in three independent efforts (Berry and Carsey; Niemi, and Powell; Snyder)—to gather legislative election data for all states and elections since 1988. In addition, Berry and Carsey (2005) cleaned the original dataset to make it more accurate and usable; their corrections led to the release of a revised ICPSR dataset (Study #3938). The culmination of these efforts is a dataset containing information about general elections for state legislative seats from 1967 to 2003, now available through ICPSR (Study 21480).
The present essay briefly examines evidence for the development of the mendicant orders, focusing on their relationship to important members of the middle and upper classes in the communes as one of the chief ways in which they gained popularity and public support. These orders came into existence between the late twelfth century and the latter half of the thirteenth. Their increased involvement with the laity was both a direct product of their concern with the needs of the contemporary church and a source of conflict between them and the existing monastic and diocesan clergy. The experience of the Humiliati in various dioceses in northern Italy illustrates an important point, namely the growing divisions within the church and the tendency to label various groups as heretical. The condemnation of the Humiliati and other groups by Pope Lucius III in Verona in 1183 is a sign of the increasing sensitivity to the danger of heresy among the laity within the leadership of the church.
The National Science Foundation created the National Science Digital Library (NSDL) in order to establish a technical, communal, and organizational framework for access to high quality resources and tools that support innovations in teaching and learning at all levels of science, technology, engineering, and mathematics education. As part of the NSDL, the Materials Digital Library (MatDL) Pathway focuses specifically on serving the materials science (MS) community with a target audience that includes MS undergraduate and graduate students, educators, and researchers. MatDL is a collaborative effort involving the Materials Science and Engineering Laboratory at the National Institute of Standards and Technology, Kent State University, Massachusetts Institute of Technology, University of Michigan, Iowa State University, and Purdue University. Our network of collaborations also includes a Nanoscience Interdisciplinary Research Team, Materials Research Science and Engineering Center, and International Materials Institute. A primary goal of MatDL is to bring materials science research and education closer together. MatDL provides innovative uses of digital libraries and the web as educational media in the MS community with particular emphasis on providing: 1) tools to describe, manage, exchange, archive, and disseminate scientific data 2) workspace for open access development of modeling and simulation tools 3) services and content for virtual labs in large undergraduate introductory science courses, and 4) workspace for collaborative development of core undergraduate MS teaching resources for emerging areas. This paper will provide an overview of the NSDL MatDL Pathway, details about specific aspects of the project, as well as interactions between research and education.